Model-Based Tools for Pharmaceutical Manufacturing Processes
Material type:
ArticleLanguage: English Publication details: MDPI - Multidisciplinary Digital Publishing Institute 2020Description: 1 electronic resource (188 p.)ISBN: - books978-3-03928-425-2
- 9783039284245
- 9783039284252
- n/a
- sensitivity analysis
- parametric probability-box
- non-isothermal modelling
- dynamic optimisation
- batch-to-batch variation
- pharmaceutical manufacturing
- process kinetics
- flowsheet modeling
- continuous manufacturing
- MATLAB Production Server
- flexibility analysis
- polynomial chaos
- probabilistic design space
- bypassing
- ODE model
- enzymatic reaction
- enzymatic synthesis
- parameter estimation
- freeze-drying
- reversible reaction
- diffusion of innovation
- multi-objective decision-making
- software development
- continuous stirred tank reactor
- parenteral manufacturing
- wet granulation
- spectroscopic assay
- process design
- dynamic modelling
- quality by design
- Fourier analysis
- residence time distribution
- point estimate method
- model integration
- global optimization
- robust process design
- pharmaceutical processes
- return on investment
- Amoxicillin
- pyrimidine-nucleoside phosphorylase
- spray drying
- single-use technology
- global sensitivity analysis
- process modeling
Open Access star Unrestricted online access
The Special Issue on “Model-Based Tools for Pharmaceutical Manufacturing Processes” will curate novel advances in the development and application of model-based tools to address ever-present challenges of the traditional pharmaceutical manufacturing practice as well as new trends. This book provides a collection of nine papers on original advances in the model-based process unit, system-level, quality-by-design under uncertainty, and decision-making applications of pharmaceutical manufacturing processes.
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