Recent Advances in Biocatalysis and Metabolic Engineering for Biomanufacturing
Lee, Eun Yeol
Recent Advances in Biocatalysis and Metabolic Engineering for Biomanufacturing - MDPI - Multidisciplinary Digital Publishing Institute 2019 - 1 electronic resource (278 p.)
Open Access
The use of biocatalysts, including enzymes and metabolically engineered cells, has attracted a great deal of attention in the chemical and bio-industry, because biocatalytic reactions can be conducted under environmentally-benign conditions and in more sustainable ways. The catalytic efficiency and chemo-, regio-, and stereo-selectivity of enzymes can be enhanced and modulated using protein engineering. Metabolic engineering seeks to enhance cellular biosynthetic productivity of target metabolites via controlling and redesigning metabolic pathways using multi-omics analysis, genome-scale modeling, metabolic flux control, and reconstruction of novel pathways. The aim of this book is to cover the recent advances in biocatalysis and metabolic engineering for biomanufacturing of biofuels, chemicals, biomaterials, and pharmaceuticals. Reviews and original research articles on the development of new strategies to improve the catalytic efficiency of enzymes, biosynthetic capability of cell factories, and their applications in production of various bioproducts and chemicals are included.
Creative Commons
English
books978-3-03921-575-1 9783039215751 9783039215744
10.3390/books978-3-03921-575-1 doi
n/a fluorescein diacetate Methylosinus sporium strain 5 soluble methane monooxygenase tunable expression system FTIR spectroscopy mevalonate kinase 1 poly(ethylene glycol) tetraethylene glycol review mevalonate (MVA) biofilm 5-hydroxymethylfurfural polymer functionalization microbial production microbial cell factory bio-hydrogen redox enzymes specific recognition fed-batch fermentation monoterpene Vitreoscilla Pvgb bioreactor 3-hydroxypropionic acid cascade reactions synthetic biology aerobic methane bioconversion starch hydrolysis CYP153A MEP pathway cross-linked enzyme aggregate interfacial activation expression vectors Combi-CLEAs polyethyleneimine bovine serum albumin polyurethane foam 12-hydroxydodecanoic acid MEV pathway amyloglucosidase total enzymatic activity Nylon 12 biocatalytic reaction Myceliophthora whole-cell biotransformation magnetic nanoparticles lipase immobilization Methanosarcina mazei biocatalysis acetate vgb C–H activation artificial self-sufficient P450 whole cell bioplastics Corynebacterium glutamicum chemicals addition enzyme modulation Eversa enzyme stabilization biocatalysts prokaryotic microbial factory synthetic metabolic pathways mannose immobilization (?)-?-bisabolol hydrogenase O2 activation string film reactor fatty acid synthesis ?-aminododecanoic acid transesterification mass transfer performance dodecanoic acid metabolic engineering glyoxal oxidase small molecules Candida antarctica Lipase B
Recent Advances in Biocatalysis and Metabolic Engineering for Biomanufacturing - MDPI - Multidisciplinary Digital Publishing Institute 2019 - 1 electronic resource (278 p.)
Open Access
The use of biocatalysts, including enzymes and metabolically engineered cells, has attracted a great deal of attention in the chemical and bio-industry, because biocatalytic reactions can be conducted under environmentally-benign conditions and in more sustainable ways. The catalytic efficiency and chemo-, regio-, and stereo-selectivity of enzymes can be enhanced and modulated using protein engineering. Metabolic engineering seeks to enhance cellular biosynthetic productivity of target metabolites via controlling and redesigning metabolic pathways using multi-omics analysis, genome-scale modeling, metabolic flux control, and reconstruction of novel pathways. The aim of this book is to cover the recent advances in biocatalysis and metabolic engineering for biomanufacturing of biofuels, chemicals, biomaterials, and pharmaceuticals. Reviews and original research articles on the development of new strategies to improve the catalytic efficiency of enzymes, biosynthetic capability of cell factories, and their applications in production of various bioproducts and chemicals are included.
Creative Commons
English
books978-3-03921-575-1 9783039215751 9783039215744
10.3390/books978-3-03921-575-1 doi
n/a fluorescein diacetate Methylosinus sporium strain 5 soluble methane monooxygenase tunable expression system FTIR spectroscopy mevalonate kinase 1 poly(ethylene glycol) tetraethylene glycol review mevalonate (MVA) biofilm 5-hydroxymethylfurfural polymer functionalization microbial production microbial cell factory bio-hydrogen redox enzymes specific recognition fed-batch fermentation monoterpene Vitreoscilla Pvgb bioreactor 3-hydroxypropionic acid cascade reactions synthetic biology aerobic methane bioconversion starch hydrolysis CYP153A MEP pathway cross-linked enzyme aggregate interfacial activation expression vectors Combi-CLEAs polyethyleneimine bovine serum albumin polyurethane foam 12-hydroxydodecanoic acid MEV pathway amyloglucosidase total enzymatic activity Nylon 12 biocatalytic reaction Myceliophthora whole-cell biotransformation magnetic nanoparticles lipase immobilization Methanosarcina mazei biocatalysis acetate vgb C–H activation artificial self-sufficient P450 whole cell bioplastics Corynebacterium glutamicum chemicals addition enzyme modulation Eversa enzyme stabilization biocatalysts prokaryotic microbial factory synthetic metabolic pathways mannose immobilization (?)-?-bisabolol hydrogenase O2 activation string film reactor fatty acid synthesis ?-aminododecanoic acid transesterification mass transfer performance dodecanoic acid metabolic engineering glyoxal oxidase small molecules Candida antarctica Lipase B