Classical Swine Fever

Wang, Fun-In

Classical Swine Fever - Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2021 - 1 electronic resource (226 p.)

Open Access

This book focuses on the “disease aspects” of classical swine fever (CSF). The epidemiological pattern of the reemergence of CSF from wild boars and its spread to neighboring domestic pigs provides useful information for policy makers. The recent advances in diagnostics and vaccines and how each type of vaccine should be appropriately used in various field situations provide useful information for practicing veterinarians and laboratory scientists, for example, whether the vaccine virus attenuated enough to not cross the placenta to avoid sequelae, how innocuous samples like serum should be cautiously treated to avoid risk of virus spread, how various genotypes of the CSF virus evolve and compete to survive in the field, and how the CSF virus molecularly manipulates normal cell biological processes for its own advantage to survive. Phylogenetic analyses help in tracing the origin of the CSF virus responsible for each outbreak. Overall, readers should be impressed by the capabilities of CFS in pigs. We hope that this book can be a useful reference for all colleagues, whether in CSF-free or CSF-affected parts of the world.


Creative Commons


English

books978-3-03943-810-5 9783039438099 9783039438105

10.3390/books978-3-03943-810-5 doi


Medicine

classical swine fever spatio-temporal analysis wild boar transboundary diseases classical swine fever virus apoptosis autophagy pyroptosis pathogenesis classical swine fever virus (CSFV) LOM vaccine strain Jeju LOM strain omega value transmission pestivirus Flaviviridae virus inactivation complement inactivation detergent Tween20 antibody detection safety sample transport CSFV pathogenicity MLV-LOM SPF pig Japan space–time analysis genotype virulence E2 gene phylogenetic tree border disease bovine viral diarrhea serum neutralization test reporter virus antibody E2 virus shift viral replication dual infections trans-placental transmission persistent congenital infection foetal immune response replication sows porcine reproductive and respiratory syndrome virus quantitative PCR modified live vaccine E2 subunit vaccine swine genome phylogeny diversity immunobiology diagnosis vaccines publication bias prevalence meta-analysis India laboratory diagnosis technologies future perspectives n/a subgenotype 2.1c subgenotype 2.1d China