Feature Paper in Antibiotics for 2019
Lipman, Jeffrey
Feature Paper in Antibiotics for 2019 - Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2020 - 1 electronic resource (282 p.)
Open Access
There has been much speculation about a possible antibiotic Armageddon; this would be the result of having untreatable post-operative infections, and similarly untreatable complications after chemotherapy. The now famous “O’Neill Report” (https://amr-review.org/) suggests that more people could die from resistant bacterial infections by 2050 than from cancer. We are still learning about all the subtle drivers of antibiotic resistance, and realizing that we need a single “whole of health” co-ordinated policy. We ingest what we sometimes feed to animals. There do not seem to be any new classes of antibiotics on our horizon. Perhaps something that has been around “forever” will come to our rescue—bacteriophages! Nevertheless, we have to do things differently, use antibiotics appropriately, for the correct indication, for the correct duration and with the correct dose, and with that, practice good antibiotic stewardship. Whilst by no means comprehensive, this book does cover some of the many topics of antibiotic stewardship. It also addresses some of the older antibiotics, some new combinations, and even some new agents. Last, and by no means least, there are two excellent articles on bacteriophages.
Creative Commons
English
books978-3-03943-123-6 9783039431229 9783039431236
10.3390/books978-3-03943-123-6 doi
Medicine
Antimicrobial resistance antibiotics antimicrobial stewardship inappropriate prescribing days of therapy Start Smart then Focus piperine piperlongumine antibacterial antifungal synergy non-target feed florfenicol thiamfenicol chloramfenicol HPLC–MS/MS validation swine out-of-hours care primary care quality of care quality indicators practitioners cooperative antibiotic stewardship fluoroquinolones guidelines urinary tract infections quality improvement general practitioners guideline health inequalities health equity assessment tool public health Enterobacteriaceae carbapenem-resistant CRE antibiotic resistance antimicrobials bacteriophages biofilms novel antimicrobials Antibiotics resistance broad-spectrum agents hospital epidemiology antibiotic utilization infection control infection prevention Pseudomonas aeruginosa Acinetobacter baumannii extended-spectrum beta-lactamases carbapenem-resistant Enterobacteriaceae methicillin-resistant Staphylococcus aureus clinical trials infectious disease phage therapy silver complexes camphorimine anti-Candida activity antifungals antibacterials efflux inhibitors efflux pumps erm(41) mutations mycobacteria verapamil actinomycetes bioactivity polyketides polyketide synthases biosynthesis antimicrobial resistance economic evaluation cost-utility analysis cost-effectiveness analysis policy analysis One Health Singapore antibiotic prescribing implementation behavior change stakeholder consultation n/a
Feature Paper in Antibiotics for 2019 - Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2020 - 1 electronic resource (282 p.)
Open Access
There has been much speculation about a possible antibiotic Armageddon; this would be the result of having untreatable post-operative infections, and similarly untreatable complications after chemotherapy. The now famous “O’Neill Report” (https://amr-review.org/) suggests that more people could die from resistant bacterial infections by 2050 than from cancer. We are still learning about all the subtle drivers of antibiotic resistance, and realizing that we need a single “whole of health” co-ordinated policy. We ingest what we sometimes feed to animals. There do not seem to be any new classes of antibiotics on our horizon. Perhaps something that has been around “forever” will come to our rescue—bacteriophages! Nevertheless, we have to do things differently, use antibiotics appropriately, for the correct indication, for the correct duration and with the correct dose, and with that, practice good antibiotic stewardship. Whilst by no means comprehensive, this book does cover some of the many topics of antibiotic stewardship. It also addresses some of the older antibiotics, some new combinations, and even some new agents. Last, and by no means least, there are two excellent articles on bacteriophages.
Creative Commons
English
books978-3-03943-123-6 9783039431229 9783039431236
10.3390/books978-3-03943-123-6 doi
Medicine
Antimicrobial resistance antibiotics antimicrobial stewardship inappropriate prescribing days of therapy Start Smart then Focus piperine piperlongumine antibacterial antifungal synergy non-target feed florfenicol thiamfenicol chloramfenicol HPLC–MS/MS validation swine out-of-hours care primary care quality of care quality indicators practitioners cooperative antibiotic stewardship fluoroquinolones guidelines urinary tract infections quality improvement general practitioners guideline health inequalities health equity assessment tool public health Enterobacteriaceae carbapenem-resistant CRE antibiotic resistance antimicrobials bacteriophages biofilms novel antimicrobials Antibiotics resistance broad-spectrum agents hospital epidemiology antibiotic utilization infection control infection prevention Pseudomonas aeruginosa Acinetobacter baumannii extended-spectrum beta-lactamases carbapenem-resistant Enterobacteriaceae methicillin-resistant Staphylococcus aureus clinical trials infectious disease phage therapy silver complexes camphorimine anti-Candida activity antifungals antibacterials efflux inhibitors efflux pumps erm(41) mutations mycobacteria verapamil actinomycetes bioactivity polyketides polyketide synthases biosynthesis antimicrobial resistance economic evaluation cost-utility analysis cost-effectiveness analysis policy analysis One Health Singapore antibiotic prescribing implementation behavior change stakeholder consultation n/a