Multiscale Modeling of Cardiac Electrophysiology: Adaptation to Atrial and Ventricular Rhythm Disorders and Pharmacological Treatment

Wilhelms, Mathias

Multiscale Modeling of Cardiac Electrophysiology: Adaptation to Atrial and Ventricular Rhythm Disorders and Pharmacological Treatment - KIT Scientific Publishing 2013 - 1 electronic resource (IX, 181 p. p.)

Open Access

Multiscale modeling of cardiac electrophysiology helps to better understand the underlying mechanisms of atrial fibrillation, acute cardiac ischemia and pharmacological treatment. For this purpose, measurement data reflecting these conditions have to be integrated into models of cardiac electrophysiology. Several methods for this model adaptation are introduced in this thesis. The resulting effects are investigated in multiscale simulations ranging from the ion channel up to the body surface.


Creative Commons


English

KSP/1000035360 9783731500452

10.5445/KSP/1000035360 doi

acute cardiac ischemia parameter adaptation pharmacological therapy atrial fibrillation cardiac modeling