Imaging Synapse Structure and Function (Record no. 41336)

MARC details
000 -LEADER
fixed length control field 02981naaaa2200385uu 4500
001 - CONTROL NUMBER
control field https://directory.doabooks.org/handle/20.500.12854/49956
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20220219201941.0
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 978-2-88945-175-3
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9782889451753
024 7# - OTHER STANDARD IDENTIFIER
Standard number or code 10.3389/978-2-88945-175-3
Terms of availability doi
041 0# - LANGUAGE CODE
Language code of text/sound track or separate title English
042 ## - AUTHENTICATION CODE
Authentication code dc
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name George J. Augustine
Relationship auth
245 10 - TITLE STATEMENT
Title Imaging Synapse Structure and Function
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Name of publisher, distributor, etc. Frontiers Media SA
Date of publication, distribution, etc. 2017
300 ## - PHYSICAL DESCRIPTION
Extent 1 electronic resource (125 p.)
506 0# - RESTRICTIONS ON ACCESS NOTE
Terms governing access Open Access
Source of term star
Standardized terminology for access restriction Unrestricted online access
520 ## - SUMMARY, ETC.
Summary, etc. Development of new imaging technologies in recent years has transformed neuroscience in profound ways. Following on the heels of the revolution based on the Green Fluorescent Protein, refined genetically-encoded fluorescent reporters and genetic targeting strategies now enable optical recording of synaptic transmission in defined neuronal populations at speeds approaching the enviable temporal resolution of electrophysiology. Super-resolution light microscopy permits observation of synapses and their molecular machinery at sub-diffraction resolution. At the ultrastructural level, automated forms of electron microscopy, improvements in specimen fixation methods, and recent efforts to correlate data from light and electron micrographs now make the reconstruction of functional neural circuits a reality. Finally, the use of optogenetic actuators, such as channelrhodopsins, allows precise temporal and spatial manipulation of neuronal activity and is revealing profound insights into the organization of neural circuits and their roles in behavior. This research topic highlights recent advances in both light and electron microscopy, with a specific focus on approaches that combine innovations from several different fields to obtain novel information about synapse structure and function. We are confident that this collection of articles - three original research papers, six reviews, one methods paper and one perspective article - will enable neuroscientists to achieve the next generation of experiments aimed at cracking the neural code.
540 ## - TERMS GOVERNING USE AND REPRODUCTION NOTE
Terms governing use and reproduction Creative Commons
Use and reproduction rights https://creativecommons.org/licenses/by/4.0/
Source of term cc
-- https://creativecommons.org/licenses/by/4.0/
546 ## - LANGUAGE NOTE
Language note English
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term connectomics
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term super-resolution
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term optogenetics
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Uncontrolled term Schizophrenia
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Uncontrolled term metabotropic glutamate receptors
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Uncontrolled term brain circuits
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Uncontrolled term functional imaging
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Uncontrolled term Electron microscopy
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Uncontrolled term calcium imaging
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Uncontrolled term Synaptic Transmission
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term synaptic vesicle trafficking
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Marc Fivaz
Relationship auth
856 40 - ELECTRONIC LOCATION AND ACCESS
Host name www.oapen.org
Uniform Resource Identifier <a href="http://journal.frontiersin.org/researchtopic/4215/imaging-synapse-structure-and-function">http://journal.frontiersin.org/researchtopic/4215/imaging-synapse-structure-and-function</a>
Access status 0
Public note DOAB: download the publication
856 40 - ELECTRONIC LOCATION AND ACCESS
Host name www.oapen.org
Uniform Resource Identifier <a href="https://directory.doabooks.org/handle/20.500.12854/49956">https://directory.doabooks.org/handle/20.500.12854/49956</a>
Access status 0
Public note DOAB: description of the publication

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