Neural Circuitry of Behavioral Flexibility: Dopamine and Related Systems (Record no. 41394)
[ view plain ]
| 000 -LEADER | |
|---|---|
| fixed length control field | 03207naaaa2200373uu 4500 |
| 001 - CONTROL NUMBER | |
| control field | https://directory.doabooks.org/handle/20.500.12854/54469 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20220219202037.0 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 978-2-88919-795-8 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9782889197958 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.3389/978-2-88919-795-8 |
| Terms of availability | doi |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | English |
| 042 ## - AUTHENTICATION CODE | |
| Authentication code | dc |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Matthew R. Roesch |
| Relationship | auth |
| 245 10 - TITLE STATEMENT | |
| Title | Neural Circuitry of Behavioral Flexibility: Dopamine and Related Systems |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Name of publisher, distributor, etc. | Frontiers Media SA |
| Date of publication, distribution, etc. | 2016 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 1 electronic resource (165 p.) |
| 506 0# - RESTRICTIONS ON ACCESS NOTE | |
| Terms governing access | Open Access |
| Source of term | star |
| Standardized terminology for access restriction | Unrestricted online access |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Decades of research have identified a role for dopamine neurotransmission in prefrontal cortical function and flexible cognition. Abnormal dopamine neurotransmission underlies many cases of cognitive dysfunction. New techniques using optogenetics have allowed for ever more precise functional segregation of areas within the prefrontal cortex, which underlie separate cognitive functions. Learning theory predictions have provided a very useful framework for interpreting the neural activity of dopamine neurons, yet even dopamine neurons present a range of responses, from salience to prediction error signaling. The functions of areas like the Lateral Habenula have been recently described, and its role, presumed to be substantial, is largely unknown. Many other neural systems interact with the dopamine system, like cortical GABAergic interneurons, making it critical to understand those systems and their interactions with dopamine in order to fully appreciate dopamine's role in flexible behavior. Advances in human clinical research, like exome sequencing, are driving experimental hypotheses which will lead to fruitful new research directions, but how do (or should?) these clinical findings inform basic research? Following new information from these techniques, we may begin to develop a fresh understanding of human disease states which will inform novel treatment possibilities. However, we need an operational framework with which to interpret these new findings. Therefore, the purpose of this Research Topic is to integrate what we know of dopamine, the prefrontal cortex and flexible behavior into a clear framework, which will illuminate clear, testable directions for future research. |
| 540 ## - TERMS GOVERNING USE AND REPRODUCTION NOTE | |
| Terms governing use and reproduction | Creative Commons |
| Use and reproduction rights | https://creativecommons.org/licenses/by/4.0/ |
| Source of term | cc |
| -- | https://creativecommons.org/licenses/by/4.0/ |
| 546 ## - LANGUAGE NOTE | |
| Language note | English |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | behavioral flexibility |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Dopamine |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | medial prefrontal cortex (mPFC) |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Attentional set-shifting |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | basal forebrain |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | anterior cingulate cortex (ACC) |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | endocannabinoid system |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | lateral habenula (LHb) |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Locus coeruleus (LC) |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | motivational salience |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Gregory B. Bissonette |
| Relationship | auth |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Host name | www.oapen.org |
| Uniform Resource Identifier | <a href="http://journal.frontiersin.org/researchtopic/3523/neural-circuitry-of-behavioral-flexibility-dopamine-and-related-systems">http://journal.frontiersin.org/researchtopic/3523/neural-circuitry-of-behavioral-flexibility-dopamine-and-related-systems</a> |
| Access status | 0 |
| Public note | DOAB: download the publication |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Host name | www.oapen.org |
| Uniform Resource Identifier | <a href="https://directory.doabooks.org/handle/20.500.12854/54469">https://directory.doabooks.org/handle/20.500.12854/54469</a> |
| Access status | 0 |
| Public note | DOAB: description of the publication |
No items available.