Pathophysiological Mechanisms of Sarcopenia in Aging and in Muscular Dystrophy: A Translational Approach (Record no. 42066)

MARC details
000 -LEADER
fixed length control field 02140naaaa2200385uu 4500
001 - CONTROL NUMBER
control field https://directory.doabooks.org/handle/20.500.12854/55788
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20220219203321.0
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 978-2-88919-684-5
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9782889196845
024 7# - OTHER STANDARD IDENTIFIER
Standard number or code 10.3389/978-2-88919-684-5
Terms of availability doi
041 0# - LANGUAGE CODE
Language code of text/sound track or separate title English
042 ## - AUTHENTICATION CODE
Authentication code dc
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name Paolo Bonaldo
Relationship auth
245 10 - TITLE STATEMENT
Title Pathophysiological Mechanisms of Sarcopenia in Aging and in Muscular Dystrophy: A Translational Approach
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Name of publisher, distributor, etc. Frontiers Media SA
Date of publication, distribution, etc. 2015
300 ## - PHYSICAL DESCRIPTION
Extent 1 electronic resource (248 p.)
506 0# - RESTRICTIONS ON ACCESS NOTE
Terms governing access Open Access
Source of term star
Standardized terminology for access restriction Unrestricted online access
520 ## - SUMMARY, ETC.
Summary, etc. Loss of muscle mass and increased fibrosis characterize both sarcopenia of aging and muscular dystrophy. Research is increasingly showing that these two conditions also share several pathophysiological mechanisms, including mitochondrial dysfunction, increased apoptosis, abnormal modulation of autophagy, decline in satellite cells, increased generation of reactive oxygen species, and abnormal regulation of signaling and stress response pathways. This Research Topic will cover several mechanisms involved in aging and dystrophic sarcopenia and explore the therapeutic potential of various strategies for intervention.
540 ## - TERMS GOVERNING USE AND REPRODUCTION NOTE
Terms governing use and reproduction Creative Commons
Use and reproduction rights https://creativecommons.org/licenses/by/4.0/
Source of term cc
-- https://creativecommons.org/licenses/by/4.0/
546 ## - LANGUAGE NOTE
Language note English
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term Aging sarcopenia
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Uncontrolled term muscular dystrophy
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Uncontrolled term Mitochondrial dysfunction
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Uncontrolled term therapy
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Uncontrolled term skeletal muscle
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Uncontrolled term Autophagy
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term Animal Models
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term Apoptosis
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term satellite cells
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term muscle imaging
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Luciano Merlini
Relationship auth
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Emanuele Marzetti
Relationship auth
856 40 - ELECTRONIC LOCATION AND ACCESS
Host name www.oapen.org
Uniform Resource Identifier <a href="http://journal.frontiersin.org/researchtopic/2299/pathophysiological-mechanisms-of-sarcopenia-in-aging-and-in-muscular-dystrophy-a-translational-appro">http://journal.frontiersin.org/researchtopic/2299/pathophysiological-mechanisms-of-sarcopenia-in-aging-and-in-muscular-dystrophy-a-translational-appro</a>
Access status 0
Public note DOAB: download the publication
856 40 - ELECTRONIC LOCATION AND ACCESS
Host name www.oapen.org
Uniform Resource Identifier <a href="https://directory.doabooks.org/handle/20.500.12854/55788">https://directory.doabooks.org/handle/20.500.12854/55788</a>
Access status 0
Public note DOAB: description of the publication

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