Apoptotic Cell Clearance in Health and Disease (Record no. 47657)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02716naaaa2200373uu 4500 |
| 001 - CONTROL NUMBER | |
| control field | https://directory.doabooks.org/handle/20.500.12854/41029 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20220219222214.0 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 978-2-88945-688-8 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9782889456888 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.3389/978-2-88945-688-8 |
| Terms of availability | doi |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | English |
| 042 ## - AUTHENTICATION CODE | |
| Authentication code | dc |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Amiram Ariel |
| Relationship | auth |
| 245 10 - TITLE STATEMENT | |
| Title | Apoptotic Cell Clearance in Health and Disease |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Name of publisher, distributor, etc. | Frontiers Media SA |
| Date of publication, distribution, etc. | 2018 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 1 electronic resource (294 p.) |
| 506 0# - RESTRICTIONS ON ACCESS NOTE | |
| Terms governing access | Open Access |
| Source of term | star |
| Standardized terminology for access restriction | Unrestricted online access |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Clearance of apoptotic cells is essential for proper development, homeostasis and termination of immune responses in multicellular organisms. Thus, cellular and molecular players taking part in the sequential events of this process are of great interest. Research in the last 20 years has indicated that specific ligands and receptors take part in the attraction of immune cells toward apoptotic targets and in the interactions between apoptotic cells and professional as well as non-professional phagocytes that engulf them. Moreover, phagocytosis of apoptotic cells (efferocytosis) leads to significant phenotypic changes in the engulfing cells suggesting that it is a major fate-determining event for phagocytes. Particularly, efferocytosis has an important impact on the inflammation-resolution axis as well as embryonic development and tissue morphogenesis. Deficiencies in these processes can result in health threats, such as autoimmunity, atherosclerosis, bone loss, obesity, infertility, neurodegeneration, fibrosis and cancer. This eBook brings together 24 original research and review manuscripts that cover various aspects of apoptotic cell removal during normal development and homeostasis as well as in tumorigenesis and regenerative processes following injury. |
| 540 ## - TERMS GOVERNING USE AND REPRODUCTION NOTE | |
| Terms governing use and reproduction | Creative Commons |
| Use and reproduction rights | https://creativecommons.org/licenses/by/4.0/ |
| Source of term | cc |
| -- | https://creativecommons.org/licenses/by/4.0/ |
| 546 ## - LANGUAGE NOTE | |
| Language note | English |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Phagocytes |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | immune-regulation |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | development |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Efferocytosis |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Homeostasis |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | neurodegeneration |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | tumorigenesis |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Apoptosis |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | receptor-ligand interactions |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Kirsten Lauber |
| Relationship | auth |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Estee Kurant |
| Relationship | auth |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Host name | www.oapen.org |
| Uniform Resource Identifier | <a href="https://www.frontiersin.org/research-topics/5442/apoptotic-cell-clearance-in-health-and-disease?utm_source=G-BLO&utm_medium=WEXT&utm_campaign=ECO_FRTOP_20181000_eBook">https://www.frontiersin.org/research-topics/5442/apoptotic-cell-clearance-in-health-and-disease?utm_source=G-BLO&utm_medium=WEXT&utm_campaign=ECO_FRTOP_20181000_eBook</a> |
| Access status | 0 |
| Public note | DOAB: download the publication |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Host name | www.oapen.org |
| Uniform Resource Identifier | <a href="https://directory.doabooks.org/handle/20.500.12854/41029">https://directory.doabooks.org/handle/20.500.12854/41029</a> |
| Access status | 0 |
| Public note | DOAB: description of the publication |
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