Chapter 3 Xenotropic Murine Leukemia Virus-Related Virus as a Case Study: Using a Precautionary Risk Management Approach for Emerging Blood-Borne Pathogens in Canada (Record no. 59528)
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| fixed length control field | 04402naaaa2200481uu 4500 |
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| control field | https://directory.doabooks.org/handle/20.500.12854/33996 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 38572 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.5772/38572 |
| Terms of availability | doi |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | English |
| 042 ## - AUTHENTICATION CODE | |
| Authentication code | dc |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | PD |
| Source | bicssc |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Oraby, Tamer |
| Relationship | auth |
| 245 10 - TITLE STATEMENT | |
| Title | Chapter 3 Xenotropic Murine Leukemia Virus-Related Virus as a Case Study: Using a Precautionary Risk Management Approach for Emerging Blood-Borne Pathogens in Canada |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Name of publisher, distributor, etc. | InTechOpen |
| Date of publication, distribution, etc. | 2012 |
| 506 0# - RESTRICTIONS ON ACCESS NOTE | |
| Terms governing access | Open Access |
| Source of term | star |
| Standardized terminology for access restriction | Unrestricted online access |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | In October 2009 it was reported that 68 of 101 patients with chronic fatigue syndrome (CFS) in the United States, when tested, were infected with a novel gamma retrovirus, xenotropic murine leukemia virus-related virus (XMRV) (Lombardi et al., 2009). XMRV is a recently discovered human gammaretrovirus first described in prostate cancers that shares significant homology with murine leukemia virus (MLV) (Ursiman et al., 2006). It is known that XMRV can cause leukemias and sarcomas in several rodent, feline, and primate species but has not been shown to cause disease in humans. XMRV was detectable in the peripheral blood mononuclear cells (PBMCs) and plasma of individuals diagnosed with CFS (Lombardi et al., 2009). After this report was published there was a great deal of uncertainty surrounding this emergent virus and its involvement in the etiology of CFS. The uncertainty was, in part, due to CFS being a complex, poorly understood multi-system disorder with different disease criteria used for its diagnosis. CFS, also known as Myalgic Encephalomyelitis (ME), is a debilitating disease of unknown origin that is estimated to affect 17 million people worldwide. The initial report connecting XMRV to prostate cancers and CFS garnered significant media and scientific interest since it provided a potential Susie ElSaadany2**, Tamer Oraby1 * Daniel Krewski1, 4 and Peter R. Ganz5 1McLaughlin Centre for Population Health Risk Assessment, Institute of Population Health, University of Ottawa, Ontario, Canada 2Blood Safety Surveillance and Health Care Acquired Infections Division, Centre for Communicable Diseases and Infection Control, Public Health Agency of Canada, Ottawa, Ontario, Canada 3Aspinall and Associates, Cleveland House, High Street, and Earth Sciences, Bristol University, Bristol, United Kingdom 4Department of Epidemiology and Community Medicine, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada 5Health Canada, Director’s Office, Ottawa, Ontario, Canada ** Corresponding Author , Marian Laderoute2 , Jun Wu2 , Willy Aspinall3 , www.intechopen.com 32 The Continuum of Health Risk Assessments explanation for the disease but also an avenue for possible therapeutic treatments since XMRV is known to be susceptible to some anti-retroviral drugs (Cohen, 2011). |
| 540 ## - TERMS GOVERNING USE AND REPRODUCTION NOTE | |
| Terms governing use and reproduction | Creative Commons |
| Use and reproduction rights | https://creativecommons.org/licenses/by/3.0/ |
| Source of term | cc |
| -- | https://creativecommons.org/licenses/by/3.0/ |
| 546 ## - LANGUAGE NOTE | |
| Language note | English |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Science: general issues |
| Source of heading or term | bicssc |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | case study |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | virus |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | case study |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | virus |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Blood plasma |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Blood-borne disease |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Canada |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Chronic fatigue syndrome |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Polymerase chain reaction |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Prostate cancer |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Xenotropic murine leukemia virus-related virus |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Aspinall, Willy |
| Relationship | auth |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Wu, Jun |
| Relationship | auth |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | ElSaadany, Susie |
| Relationship | auth |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Tyshenko, Michael G. |
| Relationship | auth |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ganz, Peter R. |
| Relationship | auth |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Laderoute, Marian |
| Relationship | auth |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Krewski, Daniel |
| Relationship | auth |
| 773 10 - HOST ITEM ENTRY | |
| Host Biblionumber | OAPEN Library ID: 612629 |
| Control subfield | nnaa |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Host name | www.oapen.org |
| Uniform Resource Identifier | <a href="https://library.oapen.org/bitstream/20.500.12657/32325/1/612629.pdf">https://library.oapen.org/bitstream/20.500.12657/32325/1/612629.pdf</a> |
| Access status | 0 |
| Public note | DOAB: download the publication |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Host name | www.oapen.org |
| Uniform Resource Identifier | <a href="https://library.oapen.org/bitstream/20.500.12657/32325/1/612629.pdf">https://library.oapen.org/bitstream/20.500.12657/32325/1/612629.pdf</a> |
| Access status | 0 |
| Public note | DOAB: download the publication |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Host name | www.oapen.org |
| Uniform Resource Identifier | <a href="https://library.oapen.org/bitstream/20.500.12657/32325/1/612629.pdf">https://library.oapen.org/bitstream/20.500.12657/32325/1/612629.pdf</a> |
| Access status | 0 |
| Public note | DOAB: download the publication |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Host name | www.oapen.org |
| Uniform Resource Identifier | <a href="https://directory.doabooks.org/handle/20.500.12854/33996">https://directory.doabooks.org/handle/20.500.12854/33996</a> |
| Access status | 0 |
| Public note | DOAB: description of the publication |
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