Stem Cell and Biologic Scaffold Engineering (Record no. 61047)
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| 000 -LEADER | |
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| fixed length control field | 05201naaaa2200889uu 4500 |
| 001 - CONTROL NUMBER | |
| control field | https://directory.doabooks.org/handle/20.500.12854/60016 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20220220030154.0 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | books978-3-03921-498-3 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9783039214976 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9783039214983 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.3390/books978-3-03921-498-3 |
| Terms of availability | doi |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | English |
| 042 ## - AUTHENTICATION CODE | |
| Authentication code | dc |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Mallis, Panagiotis |
| Relationship | auth |
| 245 10 - TITLE STATEMENT | |
| Title | Stem Cell and Biologic Scaffold Engineering |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Name of publisher, distributor, etc. | MDPI - Multidisciplinary Digital Publishing Institute |
| Date of publication, distribution, etc. | 2019 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 1 electronic resource (110 p.) |
| 506 0# - RESTRICTIONS ON ACCESS NOTE | |
| Terms governing access | Open Access |
| Source of term | star |
| Standardized terminology for access restriction | Unrestricted online access |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Tissue engineering and regenerative medicine is a rapidly evolving research field which effectively combines stem cells and biologic scaffolds in order to replace damaged tissues. Biologic scaffolds can be produced through the removal of resident cellular populations using several tissue engineering approaches, such as the decellularization method. Indeed, the decellularization method aims to develop a cell-free biologic scaffold while keeping the extracellular matrix (ECM) intact. Furthermore, biologic scaffolds have been investigated for their in vitro potential for whole organ development. Currently, clinical products composed of decellularized matrices, such as pericardium, urinary bladder, small intestine, heart valves, nerve conduits, trachea, and vessels, are being evaluated for use in human clinical trials. Tissue engineering strategies require the interaction of biologic scaffolds with cellular populations. Among them, stem cells are characterized by unlimited cell division, self-renewal, and differentiation potential, distinguishing themselves as a frontline source for the repopulation of decellularized matrices and scaffolds. Under this scheme, stem cells can be isolated from patients, expanded under good manufacturing practices (GMPs), used for the repopulation of biologic scaffolds and, finally, returned to the patient. The interaction between scaffolds and stem cells is thought to be crucial for their infiltration, adhesion, and differentiation into specific cell types. In addition, biomedical devices such as bioreactors contribute to the uniform repopulation of scaffolds. Until now, remarkable efforts have been made by the scientific society in order to establish the proper repopulation conditions of decellularized matrices and scaffolds. However, parameters such as stem cell number, in vitro cultivation conditions, and specific growth media composition need further evaluation. The ultimate goal is the development of “artificial” tissues similar to native ones, which is achieved by properly combining stem cells and biologic scaffolds and thus bringing them one step closer to personalized medicine. The original research articles and comprehensive reviews in this Special Issue deal with the use of stem cells and biologic scaffolds that utilize state-of-the-art tissue engineering and regenerative medicine approaches. |
| 540 ## - TERMS GOVERNING USE AND REPRODUCTION NOTE | |
| Terms governing use and reproduction | Creative Commons |
| Use and reproduction rights | https://creativecommons.org/licenses/by-nc-nd/4.0/ |
| Source of term | cc |
| -- | https://creativecommons.org/licenses/by-nc-nd/4.0/ |
| 546 ## - LANGUAGE NOTE | |
| Language note | English |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | nerve conduit |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | tissue engineering |
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| Uncontrolled term | regenerative medicine |
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| Uncontrolled term | mixed lymphocyte reaction |
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| Uncontrolled term | histological images |
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| Uncontrolled term | future scaffold engineering |
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| Uncontrolled term | multiparameter |
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| Uncontrolled term | 3DPVS |
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| Uncontrolled term | MSCs |
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| Uncontrolled term | Wnt signaling |
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| Uncontrolled term | Mesenchymal Stromal Cells |
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| Uncontrolled term | factorial design |
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| Uncontrolled term | novel scaffold |
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| Uncontrolled term | Wharton’s Jelly tissue |
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| Uncontrolled term | stem cells |
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| Uncontrolled term | umbilical arteries |
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| Uncontrolled term | SDS |
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| Uncontrolled term | platelet rich plasma |
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| Uncontrolled term | TGF? signaling |
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| Uncontrolled term | traditional scaffold |
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| Uncontrolled term | pluripotency and commitment |
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| Uncontrolled term | tissue engineered construct |
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| Uncontrolled term | HLA-G |
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| Uncontrolled term | CHAPS |
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| Uncontrolled term | platelets |
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| Uncontrolled term | proteomic analysis |
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| Uncontrolled term | vibrating nature of universe. |
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| Uncontrolled term | VS55 |
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| Uncontrolled term | cell culture |
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| Uncontrolled term | FGF signaling |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | evolution of scaffold |
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| Uncontrolled term | dynamicity and dimensionality |
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| Uncontrolled term | fibrin gel |
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| Uncontrolled term | scaffold classification |
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| Uncontrolled term | decellularization |
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| Uncontrolled term | vitrification |
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| Uncontrolled term | seven-folder logics |
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| Uncontrolled term | IIEF-5 questionnaire |
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| Uncontrolled term | TGF-?1 |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | erectile dysfunction |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | human induced pluripotent stem cells |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | iPSCs |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | scaffolds |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Barret’s esophagus |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | nerve regeneration |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | long term storage |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | laws of system evolution |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | scaffold categorization |
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| Uncontrolled term | platelet lysate |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | 3D scaffold |
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| Uncontrolled term | esophagus |
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| Uncontrolled term | language of relativity |
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| Uncontrolled term | cord blood units |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Host name | www.oapen.org |
| Uniform Resource Identifier | <a href="https://mdpi.com/books/pdfview/book/1650">https://mdpi.com/books/pdfview/book/1650</a> |
| Access status | 0 |
| Public note | DOAB: download the publication |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Host name | www.oapen.org |
| Uniform Resource Identifier | <a href="https://directory.doabooks.org/handle/20.500.12854/60016">https://directory.doabooks.org/handle/20.500.12854/60016</a> |
| Access status | 0 |
| Public note | DOAB: description of the publication |
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