Schizophrenia: A Consequence of Gene-Environment Interactions? (Record no. 62959)

MARC details
000 -LEADER
fixed length control field 02426naaaa2200337uu 4500
001 - CONTROL NUMBER
control field https://directory.doabooks.org/handle/20.500.12854/58945
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20220220034049.0
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 978-2-88919-531-2
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9782889195312
024 7# - OTHER STANDARD IDENTIFIER
Standard number or code 10.3389/978-2-88919-531-2
Terms of availability doi
041 0# - LANGUAGE CODE
Language code of text/sound track or separate title English
042 ## - AUTHENTICATION CODE
Authentication code dc
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name Jonathon C Arnold
Relationship auth
245 10 - TITLE STATEMENT
Title Schizophrenia: A Consequence of Gene-Environment Interactions?
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Name of publisher, distributor, etc. Frontiers Media SA
Date of publication, distribution, etc. 2015
300 ## - PHYSICAL DESCRIPTION
Extent 1 electronic resource (126 p.)
506 0# - RESTRICTIONS ON ACCESS NOTE
Terms governing access Open Access
Source of term star
Standardized terminology for access restriction Unrestricted online access
520 ## - SUMMARY, ETC.
Summary, etc. Schizophrenia is a multi-factorial disease characterized by a high heritability and environmental risk factors (e.g. stress and cannabis use). In recent years, an increasing number of researchers worldwide have started investigating the ‘two-hit hypothesis’ of schizophrenia predicting that genetic and environmental risk factors interactively cause the development of the disorder. This work is starting to produce valuable new animal models and reveal novel insights into the pathophysiology of schizophrenia. Eventually, it might help advance studies of the molecular pathways involved in this mental disorder and propose more specific molecular medicine. However, the complexity of this multi-factorial line of research has also caused difficulties in data interpretation and comparison. Our research topic is intended to cover past and current directions in research dedicated to the understanding and measurement of gene-environment interactions (GxE) in schizophrenia, the neurobiological and behavioural consequences of such interactions as well as the challenges and limitations one encounters when working on complex aetiological systems.
540 ## - TERMS GOVERNING USE AND REPRODUCTION NOTE
Terms governing use and reproduction Creative Commons
Use and reproduction rights https://creativecommons.org/licenses/by/4.0/
Source of term cc
-- https://creativecommons.org/licenses/by/4.0/
546 ## - LANGUAGE NOTE
Language note English
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term environment
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term gene
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term GxE
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term Interaction
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term two hit hypothesis
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term Schizophrenia
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term animal model
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Tim Karl
Relationship auth
856 40 - ELECTRONIC LOCATION AND ACCESS
Host name www.oapen.org
Uniform Resource Identifier <a href="http://journal.frontiersin.org/researchtopic/1089/schizophrenia-a-consequence-of-gene-environment-interactions">http://journal.frontiersin.org/researchtopic/1089/schizophrenia-a-consequence-of-gene-environment-interactions</a>
Access status 0
Public note DOAB: download the publication
856 40 - ELECTRONIC LOCATION AND ACCESS
Host name www.oapen.org
Uniform Resource Identifier <a href="https://directory.doabooks.org/handle/20.500.12854/58945">https://directory.doabooks.org/handle/20.500.12854/58945</a>
Access status 0
Public note DOAB: description of the publication

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