Recent Progress in Understanding the Mechanism and Consequences of Retrotransposon Movement (Record no. 64336)

MARC details
000 -LEADER
fixed length control field 02752naaaa2200337uu 4500
001 - CONTROL NUMBER
control field https://directory.doabooks.org/handle/20.500.12854/57787
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20220220041111.0
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9783038425410
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9783038425403
041 0# - LANGUAGE CODE
Language code of text/sound track or separate title English
042 ## - AUTHENTICATION CODE
Authentication code dc
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name David J. Garfinkel (Ed.)
Relationship auth
245 10 - TITLE STATEMENT
Title Recent Progress in Understanding the Mechanism and Consequences of Retrotransposon Movement
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Name of publisher, distributor, etc. MDPI - Multidisciplinary Digital Publishing Institute
Date of publication, distribution, etc. 2017
300 ## - PHYSICAL DESCRIPTION
Extent 1 electronic resource (VIII, 194 p.)
506 0# - RESTRICTIONS ON ACCESS NOTE
Terms governing access Open Access
Source of term star
Standardized terminology for access restriction Unrestricted online access
520 ## - SUMMARY, ETC.
Summary, etc. Retrotransposons are present in essentially all eukaryotic genomes and come in two basic flavors: those that are bracketed by long terminal repeats (LTRs) and share a common ancestor with retroviruses, and non-LTR retrotransposons that have a distinct lineage and remain transpositionally active in humans. Both types of retrotransposons replicate through an RNA intermediate, stably integrate into the host genome and have accumulated to a very high copy number in mammals and certain plant species. Autonomous elements produce transcripts capable of undergoing reverse transcription, and minimally encode proteins with reverse transcriptase, integrase/endonucleolytic, and nucleic acid chaperone activities. Retrotransposons are currently distinguished from viruses, since the process of retrotransposition is not infectious. However, this boundary may prove to be provisional as we learn more about these mobile genetic elements. The goal of this Special Issue of Viruses is to highlight progress in understanding the mechanism and consequences of retrotransposon movement. Several active research areas may be covered in reviews and research articles, including the roles of cellular modulators and defense systems, retrotransposon expression and replication, retrotransposon-induced mutations and their association with human diseases, and how these widely disseminated elements mold eukaryotic genomes.
540 ## - TERMS GOVERNING USE AND REPRODUCTION NOTE
Terms governing use and reproduction Creative Commons
Use and reproduction rights https://creativecommons.org/licenses/by-nc-nd/4.0/
Source of term cc
-- https://creativecommons.org/licenses/by-nc-nd/4.0/
546 ## - LANGUAGE NOTE
Language note English
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term Non-LTR retrotransposon
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term Integration
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term Human disease
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term Endogenous retrovirus
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term Reverse transcription
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Uncontrolled term Host factors
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Uncontrolled term Genome evolution
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Uncontrolled term LTR retrotransposon
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Katarzyna J. Purzycka (Ed.)
Relationship auth
856 40 - ELECTRONIC LOCATION AND ACCESS
Host name www.oapen.org
Uniform Resource Identifier <a href="http://www.mdpi.com/books/pdfview/book/443">http://www.mdpi.com/books/pdfview/book/443</a>
Access status 0
Public note DOAB: download the publication
856 40 - ELECTRONIC LOCATION AND ACCESS
Host name www.oapen.org
Uniform Resource Identifier <a href="https://directory.doabooks.org/handle/20.500.12854/57787">https://directory.doabooks.org/handle/20.500.12854/57787</a>
Access status 0
Public note DOAB: description of the publication

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