Pattern recognition receptors and cancer (Record no. 68918)

MARC details
000 -LEADER
fixed length control field 02944naaaa2200373uu 4500
001 - CONTROL NUMBER
control field https://directory.doabooks.org/handle/20.500.12854/55828
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20220220055026.0
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 978-2-88919-674-6
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9782889196746
024 7# - OTHER STANDARD IDENTIFIER
Standard number or code 10.3389/978-2-88919-674-6
Terms of availability doi
041 0# - LANGUAGE CODE
Language code of text/sound track or separate title English
042 ## - AUTHENTICATION CODE
Authentication code dc
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name Anton G. Kutikhin
Relationship auth
245 10 - TITLE STATEMENT
Title Pattern recognition receptors and cancer
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Name of publisher, distributor, etc. Frontiers Media SA
Date of publication, distribution, etc. 2015
300 ## - PHYSICAL DESCRIPTION
Extent 1 electronic resource (201 p.)
506 0# - RESTRICTIONS ON ACCESS NOTE
Terms governing access Open Access
Source of term star
Standardized terminology for access restriction Unrestricted online access
520 ## - SUMMARY, ETC.
Summary, etc. The group of pattern recognition receptors (PRRs) includes families of Toll-like receptors (TLRs), NOD-like receptors (NLRs), C-type lectin receptors (CLRs), RIG-I-like receptors (RLRs), and AIM-2-like receptors (ALRs). Conceptually, receptors constituting these families are united by two general features. Firstly, they directly recognize common antigen determinants of virtually all classes of pathogens (so-called pathogen-associated molecular patterns, or simply PAMPs) and initiate immune response against them via specific intracellular signaling pathways. Secondly, they recognize endogenous ligands (since they are usually released during cell stress, they are called damage-associated molecular patterns, DAMPs), and, hence, PRR-mediated immune response can be activated without an influence of infectious agents. So, pattern recognition receptors play the key role performing the innate and adaptive immune response. In addition, many PRRs have a number of other vital functions apart from participation in immune response realization. The fundamental character and diversity of PRR functions have led to amazingly rapid research in this field. Such investigations are very promising for medicine as immune system plays a key role in vast majority if not all human diseases, and the process of discovering the new aspects of the immune system functioning is rapidly ongoing. The role of Toll-like receptors in cancer was analyzed in certain reviews but the data are still scattered. This collection of reviews systematizes the key information in the field.
540 ## - TERMS GOVERNING USE AND REPRODUCTION NOTE
Terms governing use and reproduction Creative Commons
Use and reproduction rights https://creativecommons.org/licenses/by/4.0/
Source of term cc
-- https://creativecommons.org/licenses/by/4.0/
546 ## - LANGUAGE NOTE
Language note English
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term Toll-Like Receptors
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term C-type lectin receptors
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term nod-like receptors
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Uncontrolled term DNA Repair
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Uncontrolled term Pattern Recognition Receptors
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Uncontrolled term Inflammation
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term RIG-I-like receptors
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term Autophagy
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term Cancer
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term Apoptosis
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Arseniy E. Yuzhalin
Relationship auth
856 40 - ELECTRONIC LOCATION AND ACCESS
Host name www.oapen.org
Uniform Resource Identifier <a href="http://journal.frontiersin.org/researchtopic/1919/pattern-recognition-receptors-and-cancer">http://journal.frontiersin.org/researchtopic/1919/pattern-recognition-receptors-and-cancer</a>
Access status 0
Public note DOAB: download the publication
856 40 - ELECTRONIC LOCATION AND ACCESS
Host name www.oapen.org
Uniform Resource Identifier <a href="https://directory.doabooks.org/handle/20.500.12854/55828">https://directory.doabooks.org/handle/20.500.12854/55828</a>
Access status 0
Public note DOAB: description of the publication

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