Chemically-Induced DNA Damage, Mutagenesis, and Cancer (Record no. 69321)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02418naaaa2200361uu 4500 |
| 001 - CONTROL NUMBER | |
| control field | https://directory.doabooks.org/handle/20.500.12854/43078 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20220220055925.0 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9783038971290 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9783038971306 |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | English |
| 042 ## - AUTHENTICATION CODE | |
| Authentication code | dc |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Takehiko Nohmi (Ed.) |
| Relationship | auth |
| 245 10 - TITLE STATEMENT | |
| Title | Chemically-Induced DNA Damage, Mutagenesis, and Cancer |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Name of publisher, distributor, etc. | MDPI - Multidisciplinary Digital Publishing Institute |
| Date of publication, distribution, etc. | 2018 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 1 electronic resource (X, 264 p.) |
| 506 0# - RESTRICTIONS ON ACCESS NOTE | |
| Terms governing access | Open Access |
| Source of term | star |
| Standardized terminology for access restriction | Unrestricted online access |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Human cancers frequently arise from exposure to chemicals, although radiation, oxidation, and genetic factors play critical roles as well. DNA damage by these agents in a cell is an important first step in the process of carcinogenesis. DNA repair processes have evolved to repair these damages. However, the replication of damaged DNA may occur frequently prior to repair, resulting in gene mutations and the generation of altered proteins. Mutations in an oncogene, a tumor-suppressor gene, or a gene that controls the cell cycle give rise to a clonal cell population with an advantage in proliferation. The complex process of carcinogenesis includes many such events, but has been generally considered to be comprised of the three main stages known as initiation, promotion, and progression, which ultimately give rise to the induction of human cancer. The articles published in this book entitled “Chemically-Induced DNA Damage, Mutagenesis, and Cancer” provide an overview on the topic of the “consequence of DNA damage” in the context of human cancer with their challenges and highlights. |
| 540 ## - TERMS GOVERNING USE AND REPRODUCTION NOTE | |
| Terms governing use and reproduction | Creative Commons |
| Use and reproduction rights | https://creativecommons.org/licenses/by-nc-nd/4.0/ |
| Source of term | cc |
| -- | https://creativecommons.org/licenses/by-nc-nd/4.0/ |
| 546 ## - LANGUAGE NOTE | |
| Language note | English |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | genotoxicity |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | chemoprevention |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | DNA damage |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | metal toxicity |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | apoptosis |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | melanoma |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | tumor cells |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | DNA repair |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | chemotherapy |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | translesion synthesis |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ashis K. Basu (Ed.) |
| Relationship | auth |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Host name | www.oapen.org |
| Uniform Resource Identifier | <a href="https://doi.org/10.3390/books978-3-03897-130-6">https://doi.org/10.3390/books978-3-03897-130-6</a> |
| Access status | 0 |
| Public note | DOAB: download the publication |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Host name | www.oapen.org |
| Uniform Resource Identifier | <a href="https://directory.doabooks.org/handle/20.500.12854/43078">https://directory.doabooks.org/handle/20.500.12854/43078</a> |
| Access status | 0 |
| Public note | DOAB: description of the publication |
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