Role of Stem Cells in Skeletal Muscle Development, Regeneration, Repair, Aging and Disease (Record no. 70671)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03207naaaa2200397uu 4500 |
| 001 - CONTROL NUMBER | |
| control field | https://directory.doabooks.org/handle/20.500.12854/58607 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20220220062945.0 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 978-2-88919-866-5 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9782889198665 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.3389/978-2-88919-866-5 |
| Terms of availability | doi |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | English |
| 042 ## - AUTHENTICATION CODE | |
| Authentication code | dc |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Pura Munoz-Canoves |
| Relationship | auth |
| 245 10 - TITLE STATEMENT | |
| Title | Role of Stem Cells in Skeletal Muscle Development, Regeneration, Repair, Aging and Disease |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Name of publisher, distributor, etc. | Frontiers Media SA |
| Date of publication, distribution, etc. | 2016 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 1 electronic resource (220 p.) |
| 506 0# - RESTRICTIONS ON ACCESS NOTE | |
| Terms governing access | Open Access |
| Source of term | star |
| Standardized terminology for access restriction | Unrestricted online access |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Adult stem cells are responsible for tissue regeneration and repair throughout life. Their quiescence or activation are tightly regulated by common signalling pathways that often recapitulate those happening during embryonic development, and thus it is important to understand their regulation not only in postnatal life, but also during foetal development. In this regard, skeletal muscle is an interesting tissue since it accounts for a large percentage of body mass (about 40%), it is highly amenable to intervention through exercise and it is also key in metabolic and physiological changes underlying frailty susceptibility in the elderly. While muscle-resident satellite cells are responsible for all myogenic activity in physiological conditions and become senescent in old age, other progenitor cells such as mesoangioblasts do seem to contribute to muscle regeneration and repair after tissue damage. Similarly, fibro-adipogenic precursor cells seem to be key in the aberrant response that fills up the space left from atrophied muscle mass and which ends up with a dysfunctional muscle having vast areas of fatty infiltration and fibrosis. The complex interplay between these stem/progenitor cell types and their niches in normal and pathological conditions throughout life are the subjects of intense investigation. This eBook highlights recent developments on the role of stem cells in skeletal muscle function, both in prenatal and postnatal life, and their regulation by transcriptional, post-transcriptional and epigenetic mechanisms. Additionally, it includes articles on interventions associated with exercise, pathological changes in neuromuscular diseases, and stem cell aging. |
| 540 ## - TERMS GOVERNING USE AND REPRODUCTION NOTE | |
| Terms governing use and reproduction | Creative Commons |
| Use and reproduction rights | https://creativecommons.org/licenses/by/4.0/ |
| Source of term | cc |
| -- | https://creativecommons.org/licenses/by/4.0/ |
| 546 ## - LANGUAGE NOTE | |
| Language note | English |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | ageing |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | satellite cell |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | pericytes |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | fibrosis |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | myogenesis |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | muscular dystrophies |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | rejuvenation |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | epigenetics |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | muscle wasting |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | sarcopenia |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Jaime J. Carvajal |
| Relationship | auth |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Adolfo Lopez de Munain |
| Relationship | auth |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ander Izeta |
| Relationship | auth |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Host name | www.oapen.org |
| Uniform Resource Identifier | <a href="http://journal.frontiersin.org/researchtopic/3021/role-of-stem-cells-in-skeletal-muscle-development-regeneration-repair-aging-and-disease">http://journal.frontiersin.org/researchtopic/3021/role-of-stem-cells-in-skeletal-muscle-development-regeneration-repair-aging-and-disease</a> |
| Access status | 0 |
| Public note | DOAB: download the publication |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Host name | www.oapen.org |
| Uniform Resource Identifier | <a href="https://directory.doabooks.org/handle/20.500.12854/58607">https://directory.doabooks.org/handle/20.500.12854/58607</a> |
| Access status | 0 |
| Public note | DOAB: description of the publication |
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