Toxins in Drug Discovery and Pharmacology (Record no. 71145)

MARC details
000 -LEADER
fixed length control field 02749naaaa2200409uu 4500
001 - CONTROL NUMBER
control field https://directory.doabooks.org/handle/20.500.12854/61071
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20220220064007.0
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9783038428619
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9783038428626
041 0# - LANGUAGE CODE
Language code of text/sound track or separate title English
042 ## - AUTHENTICATION CODE
Authentication code dc
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name Steve Peigneur (Ed.)
Relationship auth
245 10 - TITLE STATEMENT
Title Toxins in Drug Discovery and Pharmacology
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Name of publisher, distributor, etc. MDPI - Multidisciplinary Digital Publishing Institute
Date of publication, distribution, etc. 2018
300 ## - PHYSICAL DESCRIPTION
Extent 1 electronic resource (XII, 304 p.)
506 0# - RESTRICTIONS ON ACCESS NOTE
Terms governing access Open Access
Source of term star
Standardized terminology for access restriction Unrestricted online access
520 ## - SUMMARY, ETC.
Summary, etc. Venoms from marine and terrestrial animals (cone snails, scorpions, spiders, snakes, centipedes, cnidarian, etc.) can be seen as untapped cocktails of biologically active compounds that are being increasingly recognized as a new emerging source of peptide-based therapeutics. Venomous animals are considered to be specialized predators that have evolved the most sophisticated peptide chemistry and neuropharmacology for their own biological purposes by producing venoms that contain a structural and functional diversity of neurotoxins. These neurotoxins appear to be highly selective ligands for a wide range of ion channels and receptors. Therefore, they represent interesting lead compounds for the development of analgesics, anti-cancer drugs, drugs for neurological disorders such as multiple sclerosis, Parkinson' s disease, Alzheimer' s disease, and other therapeutics. This Special Issue of Toxins aims to provide a comprehensive look at toxins and toxin-inspired leads and will focus on the mechanisms of action, structure–function relationships, and evolution of pharmacologically interesting venom components, including the most recent developments related to the emergence of venoms as an underutilized source of highly evolved bioactive peptides with clinical potential.
540 ## - TERMS GOVERNING USE AND REPRODUCTION NOTE
Terms governing use and reproduction Creative Commons
Use and reproduction rights https://creativecommons.org/licenses/by-nc-nd/4.0/
Source of term cc
-- https://creativecommons.org/licenses/by-nc-nd/4.0/
546 ## - LANGUAGE NOTE
Language note English
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term calcium channels
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term acetylcholine receptors
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term peptides
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term botulinum toxins
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term TRP channels
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term spider venom peptides
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term sodium channels
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term opiate receptors
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term Antibiotics
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term cone snail venom
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term potassium channels
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term chloride ion channels
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term ASIC channels
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term NMDA receptor
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term antimicrobial peptides
856 40 - ELECTRONIC LOCATION AND ACCESS
Host name www.oapen.org
Uniform Resource Identifier <a href="http://www.mdpi.com/books/pdfview/book/608">http://www.mdpi.com/books/pdfview/book/608</a>
Access status 0
Public note DOAB: download the publication
856 40 - ELECTRONIC LOCATION AND ACCESS
Host name www.oapen.org
Uniform Resource Identifier <a href="https://directory.doabooks.org/handle/20.500.12854/61071">https://directory.doabooks.org/handle/20.500.12854/61071</a>
Access status 0
Public note DOAB: description of the publication

No items available.