Aging and Age-related Disorders: From Molecular Mechanisms to Therapies (Record no. 71188)
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| fixed length control field | 04018naaaa2200745uu 4500 |
| 001 - CONTROL NUMBER | |
| control field | https://directory.doabooks.org/handle/20.500.12854/40469 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20220220064054.0 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | books978-3-03921-356-6 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9783039213559 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9783039213566 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.3390/books978-3-03921-356-6 |
| Terms of availability | doi |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | English |
| 042 ## - AUTHENTICATION CODE | |
| Authentication code | dc |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Titorenko, Vladimir |
| Relationship | auth |
| 245 10 - TITLE STATEMENT | |
| Title | Aging and Age-related Disorders: From Molecular Mechanisms to Therapies |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Name of publisher, distributor, etc. | MDPI - Multidisciplinary Digital Publishing Institute |
| Date of publication, distribution, etc. | 2019 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 1 electronic resource (322 p.) |
| 506 0# - RESTRICTIONS ON ACCESS NOTE | |
| Terms governing access | Open Access |
| Source of term | star |
| Standardized terminology for access restriction | Unrestricted online access |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Aging of unicellular and multicellular eukaryotic organisms is a convoluted biological phenomenon, which is manifested as an age-related functional decline caused by progressive dysregulation of certain cellular and organismal processes. Many chronic diseases are associated with human aging. These aging-associated diseases include cardiovascular diseases, chronic obstructive pulmonary disease, chronic kidney disease, diabetes, osteoarthritis, osteoporosis, sarcopenia, stroke, neurodegenerative diseases (including Parkinson’s, Alzheimer’s, and Huntington’s diseases), and many forms of cancer. Studies in yeast, roundworms, fruit flies, fishes, mice, primates, and humans have provided evidence that the major aspects and basic mechanisms of aging and aging-associated pathology are conserved across phyla. The focus of this International Journal of Molecular Sciences Special Issue is on molecular and cellular mechanisms, diagnostics, and therapies and diseases of aging. Fifteen original research and review articles in this Special Issue provide important insights into how various genetic, dietary, and pharmacological interventions can affect certain longevity-defining cellular and organismal processes to delay aging and postpone the onset of age-related pathologies in evolutionarily diverse organisms. These articles outline the most important unanswered questions and directions for future research in the vibrant and rapidly evolving fields of mechanisms of biological aging, aging-associated diseases, and aging-delaying therapies. |
| 540 ## - TERMS GOVERNING USE AND REPRODUCTION NOTE | |
| Terms governing use and reproduction | Creative Commons |
| Use and reproduction rights | https://creativecommons.org/licenses/by-nc-nd/4.0/ |
| Source of term | cc |
| -- | https://creativecommons.org/licenses/by-nc-nd/4.0/ |
| 546 ## - LANGUAGE NOTE | |
| Language note | English |
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| Uncontrolled term | advanced glycated end products |
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| Uncontrolled term | microRNAs |
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| Uncontrolled term | n/a |
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| Uncontrolled term | differentiation |
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| Uncontrolled term | transcription |
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| Uncontrolled term | skin absorption |
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| Uncontrolled term | cellular quiescence |
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| Uncontrolled term | lifespan |
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| Uncontrolled term | longevity genes |
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| Uncontrolled term | protein kinases |
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| Uncontrolled term | self-renewal |
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| Uncontrolled term | circadian |
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| Uncontrolled term | blood–brain barrier |
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| Uncontrolled term | aging-related disorders |
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| Uncontrolled term | sirtuin-1 |
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| Uncontrolled term | inflammation |
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| Uncontrolled term | arterial aging |
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| Uncontrolled term | reactive oxygen species |
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| Uncontrolled term | electron microscopy |
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| Uncontrolled term | reconstructed human skin |
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| Uncontrolled term | rejuvenation |
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| Uncontrolled term | low-dose fluvastatin and valsartan combination |
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| Uncontrolled term | inflammaging |
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| Uncontrolled term | hematopoietic stem cell aging |
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| Uncontrolled term | cell cycle |
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| Uncontrolled term | mitochondria |
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| Uncontrolled term | ribose |
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| Uncontrolled term | the nervous system |
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| Uncontrolled term | nanomedicine |
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| Uncontrolled term | proteostasis |
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| Uncontrolled term | adult stem cells |
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| Uncontrolled term | immunosenescence |
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| Uncontrolled term | cell signaling |
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| Uncontrolled term | mechanisms of quiescence maintenance |
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| Uncontrolled term | metabolism |
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| Uncontrolled term | aging |
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| Uncontrolled term | melatonin |
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| Uncontrolled term | diabetes |
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| Uncontrolled term | mechanisms of quiescence entry and exit |
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| Uncontrolled term | Drosophila melanogaster |
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| Uncontrolled term | GSK3 (glycogen synthase kinase 3) |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Host name | www.oapen.org |
| Uniform Resource Identifier | <a href="https://mdpi.com/books/pdfview/book/1490">https://mdpi.com/books/pdfview/book/1490</a> |
| Access status | 0 |
| Public note | DOAB: download the publication |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Host name | www.oapen.org |
| Uniform Resource Identifier | <a href="https://directory.doabooks.org/handle/20.500.12854/40469">https://directory.doabooks.org/handle/20.500.12854/40469</a> |
| Access status | 0 |
| Public note | DOAB: description of the publication |
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