The Shaping of Cancer by the Tumour Microenvironment and Its Relevance for Cancer Therapy (Record no. 72417)
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                            | 000 -LEADER | |
|---|---|
| fixed length control field | 04794naaaa2201333uu 4500 | 
| 001 - CONTROL NUMBER | |
| control field | https://directory.doabooks.org/handle/20.500.12854/76822 | 
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20220220070906.0 | 
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | books978-3-0365-1607-3 | 
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9783036516080 | 
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9783036516073 | 
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.3390/books978-3-0365-1607-3 | 
| Terms of availability | doi | 
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | English | 
| 042 ## - AUTHENTICATION CODE | |
| Authentication code | dc | 
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | M | 
| Source | bicssc | 
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Madureira, Patrícia Alexandra Saraiva | 
| Relationship | edt | 
| 245 10 - TITLE STATEMENT | |
| Title | The Shaping of Cancer by the Tumour Microenvironment and Its Relevance for Cancer Therapy | 
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Basel, Switzerland | 
| Name of publisher, distributor, etc. | MDPI - Multidisciplinary Digital Publishing Institute | 
| Date of publication, distribution, etc. | 2021 | 
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 1 electronic resource (307 p.) | 
| 506 0# - RESTRICTIONS ON ACCESS NOTE | |
| Terms governing access | Open Access | 
| Source of term | star | 
| Standardized terminology for access restriction | Unrestricted online access | 
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | In this book, we present a compilation of original research articles as well as review articles that are focused on improving our understanding of the molecular and cellular mechanisms by which cancer cells adapt to their microenvironment. These include the interplay between cancer cells and the surrounding microenvironmental cells (e.g., macrophages, tumor-infiltrating lymphocytes and myeloid cells) and microenvironmental environments (e.g., oxidative stress, pH, hypoxia) and the implications of this dynamic interaction to tumor radioresistance, chemoresistance, invasion and metastasis. Finally, the importance and relevance of these findings are translated to cancer therapy. | 
| 540 ## - TERMS GOVERNING USE AND REPRODUCTION NOTE | |
| Terms governing use and reproduction | Creative Commons | 
| Use and reproduction rights | https://creativecommons.org/licenses/by/4.0/ | 
| Source of term | cc | 
| -- | https://creativecommons.org/licenses/by/4.0/ | 
| 546 ## - LANGUAGE NOTE | |
| Language note | English | 
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Medicine | 
| Source of heading or term | bicssc | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | hypoxia | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | macrophages | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | colon cancer | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | tumor microenvironment | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | immune cell infiltration | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | prognosis | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | feline mammary carcinoma | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | PD-1 | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | PD-L1 | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | CTLA-4 | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | TNF-α | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | biomarkers | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | immunotherapy | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | cancer | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | histone modification | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | inhibitor | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | KDM5B | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | molecular docking | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | repurposing | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | cancer acidity | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | hyperosmolarity | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | cross-presentation | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | tumour microenvironment | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | syngeneic model | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | prostate cancer | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | radiotherapy | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | preclinical modelling | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | myeloid-derived suppressor cells | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | biomarker | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | stroma | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | cancer-associated fibroblast (CAF) | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | extracellular matrix (ECM) | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | cytokine/chemokine | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | growth factors | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | pro- and anti-tumor immune cells | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | immunomodulatory roles | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | radiotherapy dose fractionation | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | radioresistance | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | radiosensitivity | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | breast cancer | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | S100A10 (p11) | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | tumor growth | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | tumor progression | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | metastasis | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | carcinoma | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | mammary gland | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | triple negative | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | pre-metastatic niche | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | pro-inflammatory cytokines | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | clinical trials | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | evolutionary therapy | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | darwinian evolution | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | cancer cells subpopulations | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | diclofenac | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | koningic acid | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | spheroid | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | 3D co-culture | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | microenvironment | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | resistance | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | myeloid cells | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | cancer development | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | molecular subtypes of pancreatic cancer | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | chemotherapy response | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | pancreatic stellate cells | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | regulatory T cells | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | tumor-associated macrophages | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | myeloid derived suppressor cells | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | glioblastoma (GB) | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Hypoxia Inducible Factor (HIF) | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | glioma stem cells (GSC) | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | oxidative stress | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | reactive oxygen species | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | plasmin | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | plasminogen | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | S100A10 | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | uPA | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | uPAR | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | PAI-1 | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | PAI-2 | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | cancer stem cells | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | cancer recurrence | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | therapeutic resistance | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | signaling pathways | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | targeted therapy | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | head and neck cancer | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | lung cancer | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | bladder cancer | 
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Madureira, Patrícia Alexandra Saraiva | 
| Relationship | oth | 
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Host name | www.oapen.org | 
| Uniform Resource Identifier | <a href="https://mdpi.com/books/pdfview/book/4271">https://mdpi.com/books/pdfview/book/4271</a> | 
| Access status | 0 | 
| Public note | DOAB: download the publication | 
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Host name | www.oapen.org | 
| Uniform Resource Identifier | <a href="https://directory.doabooks.org/handle/20.500.12854/76822">https://directory.doabooks.org/handle/20.500.12854/76822</a> | 
| Access status | 0 | 
| Public note | DOAB: description of the publication | 
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