Motor Cortex Microcircuits (Frontiers in Brain Microcircuits Series) (Record no. 73404)

MARC details
000 -LEADER
fixed length control field 02959naaaa2200337uu 4500
001 - CONTROL NUMBER
control field https://directory.doabooks.org/handle/20.500.12854/53983
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20220220073027.0
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 978-2-88919-389-9
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9782889193899
024 7# - OTHER STANDARD IDENTIFIER
Standard number or code 10.3389/978-2-88919-389-9
Terms of availability doi
041 0# - LANGUAGE CODE
Language code of text/sound track or separate title English
042 ## - AUTHENTICATION CODE
Authentication code dc
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name Takehsi Kaneko
Relationship auth
245 10 - TITLE STATEMENT
Title Motor Cortex Microcircuits (Frontiers in Brain Microcircuits Series)
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Name of publisher, distributor, etc. Frontiers Media SA
Date of publication, distribution, etc. 2015
300 ## - PHYSICAL DESCRIPTION
Extent 1 electronic resource (133 p.)
506 0# - RESTRICTIONS ON ACCESS NOTE
Terms governing access Open Access
Source of term star
Standardized terminology for access restriction Unrestricted online access
520 ## - SUMMARY, ETC.
Summary, etc. How does the motor cortex enable mammals to generate accurate, complex, and purposeful movements? A cubic millimeter of motor cortex contains roughly ~10^5 cells, an amazing ~4 Km of axons and ~0.4 Km of dendrites, somehow wired together with ~10^9 synapses. Corticospinal neurons (a.k.a. Betz cells, upper motor neurons) are a key cell type, monosynaptically conveying the output of the cortical circuit to the spinal cord circuits and lower motor neurons. But corticospinal neurons are greatly outnumbered by all the other kinds of neurons in motor cortex, which presumably also contribute crucially to the computational operations carried out for planning, executing, and guiding actions. Determining the wiring patterns, the dynamics of signaling, and how these relate to movement at the level of specific excitatory and inhibitory cell types is critically important for a mechanistic understanding of the input-output organization of motor cortex. While there is a predictive microcircuit hypothesis that relates motor learning to the operation of the cerebellar cortex, we lack such a microcircuit understanding in motor cortex and we consider microcircuits as a central research topic in the field. This Research Topic covers any issues relating to the microcircuit-level analysis of motor cortex. Contributions are welcomed from neuroscientists at all levels of investigation, from in vivo physiology and imaging in humans and monkeys, to rodent models, in vitro anatomy, electrophysiology, electroanatomy, cellular imaging, molecular biology, disease models, computational modeling, and more.
540 ## - TERMS GOVERNING USE AND REPRODUCTION NOTE
Terms governing use and reproduction Creative Commons
Use and reproduction rights https://creativecommons.org/licenses/by/4.0/
Source of term cc
-- https://creativecommons.org/licenses/by/4.0/
546 ## - LANGUAGE NOTE
Language note English
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term Motor Cortex
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Uncontrolled term intracortical connectivity
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Uncontrolled term corticospinal neurons
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Uncontrolled term directional tuning
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Uncontrolled term motor control
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Gordon M. G Shepherd
Relationship auth
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Michael Brecht
Relationship auth
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Nicholas Hatsopoulos
Relationship auth
856 40 - ELECTRONIC LOCATION AND ACCESS
Host name www.oapen.org
Uniform Resource Identifier <a href="http://journal.frontiersin.org/researchtopic/738/motor-cortex-microcircuits-frontiers-in-brain-microcircuits-series">http://journal.frontiersin.org/researchtopic/738/motor-cortex-microcircuits-frontiers-in-brain-microcircuits-series</a>
Access status 0
Public note DOAB: download the publication
856 40 - ELECTRONIC LOCATION AND ACCESS
Host name www.oapen.org
Uniform Resource Identifier <a href="https://directory.doabooks.org/handle/20.500.12854/53983">https://directory.doabooks.org/handle/20.500.12854/53983</a>
Access status 0
Public note DOAB: description of the publication

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