Spatial memory - a unique window into healthy and pathological ageing (Record no. 74239)

MARC details
000 -LEADER
fixed length control field 03077naaaa2200337uu 4500
001 - CONTROL NUMBER
control field https://directory.doabooks.org/handle/20.500.12854/59794
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20220220074953.0
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 978-2-88919-386-8
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9782889193868
024 7# - OTHER STANDARD IDENTIFIER
Standard number or code 10.3389/978-2-88919-386-8
Terms of availability doi
041 0# - LANGUAGE CODE
Language code of text/sound track or separate title English
042 ## - AUTHENTICATION CODE
Authentication code dc
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name Emma R. Wood
Relationship auth
245 10 - TITLE STATEMENT
Title Spatial memory - a unique window into healthy and pathological ageing
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Name of publisher, distributor, etc. Frontiers Media SA
Date of publication, distribution, etc. 2015
300 ## - PHYSICAL DESCRIPTION
Extent 1 electronic resource (122 p.)
506 0# - RESTRICTIONS ON ACCESS NOTE
Terms governing access Open Access
Source of term star
Standardized terminology for access restriction Unrestricted online access
520 ## - SUMMARY, ETC.
Summary, etc. The global population aged over 60 is set to rise dramatically in the coming decades. In many countries, the older population now faces the prospect of spending a quarter of their lives aged over 65, and a significant proportion will have to cope with cognitive decline associated with normal ageing or with dementia disorders. Given that these fundamental demographic changes will pose a significant challenge to health care systems, a detailed understanding of age-related cognitive and neurobiological changes is essential in helping elderly populations maintain cognitive performance. In addition, developing sensitive biomarkers to identify those at risk of developing dementia is crucial for early and effective interventions. To make inferences about the ageing process from the animal model back to the human, rigorous behavioral paradigms must be used to ensure that the same function is being examined across species. Given that similar navigational paradigms can easily be applied to humans and animals, recent years have seen an expansion of studies attempting to bridge the gap between age-related changes in animal and human spatial cognition. These studies begin to suggest that disruptions in spatial computations are among the earliest indicators of impending cognitive decline. In addition, although many animal studies have identified pathological mechanisms with paradigms involving spatial navigation, these mechanisms support many nonspatial cognitive functions as well. As a consequence, a successful characterization of how spatial processing changes in the ageing brain could reveal fundamental effects of cognitive ageing that could inform about general mechanisms underlying decline in perception, mnemonic processing and multisensory integration.
540 ## - TERMS GOVERNING USE AND REPRODUCTION NOTE
Terms governing use and reproduction Creative Commons
Use and reproduction rights https://creativecommons.org/licenses/by/4.0/
Source of term cc
-- https://creativecommons.org/licenses/by/4.0/
546 ## - LANGUAGE NOTE
Language note English
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term Neuroscience
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term spatial navigation
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term Humans
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term Aging
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term Animal Models
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term Dementia
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Thomas Wolbers
Relationship auth
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Paul A. Dudchenko
Relationship auth
856 40 - ELECTRONIC LOCATION AND ACCESS
Host name www.oapen.org
Uniform Resource Identifier <a href="http://journal.frontiersin.org/researchtopic/533/spatial-memory---a-unique-window-into-healthy-and-pathological-ageing">http://journal.frontiersin.org/researchtopic/533/spatial-memory---a-unique-window-into-healthy-and-pathological-ageing</a>
Access status 0
Public note DOAB: download the publication
856 40 - ELECTRONIC LOCATION AND ACCESS
Host name www.oapen.org
Uniform Resource Identifier <a href="https://directory.doabooks.org/handle/20.500.12854/59794">https://directory.doabooks.org/handle/20.500.12854/59794</a>
Access status 0
Public note DOAB: description of the publication

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