Redox Regulation in Skeletal Muscle Aging and Exercise (Record no. 74992)

MARC details
000 -LEADER
fixed length control field 02594naaaa2200337uu 4500
001 - CONTROL NUMBER
control field https://directory.doabooks.org/handle/20.500.12854/57918
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20220220080619.0
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 978-2-88945-196-8
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9782889451968
024 7# - OTHER STANDARD IDENTIFIER
Standard number or code 10.3389/978-2-88945-196-8
Terms of availability doi
041 0# - LANGUAGE CODE
Language code of text/sound track or separate title English
042 ## - AUTHENTICATION CODE
Authentication code dc
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name Brian McDonagh
Relationship auth
245 10 - TITLE STATEMENT
Title Redox Regulation in Skeletal Muscle Aging and Exercise
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Name of publisher, distributor, etc. Frontiers Media SA
Date of publication, distribution, etc. 2017
300 ## - PHYSICAL DESCRIPTION
Extent 1 electronic resource (101 p.)
506 0# - RESTRICTIONS ON ACCESS NOTE
Terms governing access Open Access
Source of term star
Standardized terminology for access restriction Unrestricted online access
520 ## - SUMMARY, ETC.
Summary, etc. Skeletal muscle represents the largest organ of the human body and comprises about 40% of total body mass in humans. Even in people who ‘age well’, there is a noticeable loss of muscle strength and function that accelerates dramatically after the age of 60, a major factor in the reduction in life quality for the aging population. One of the most effective interventions to maintain muscle mass and function is through exercise. Skeletal muscle generates reactive oxygen and reactive nitrogen (ROS/RNS) species in response to muscle contractions. The concentration and species of ROS/RNS generated can depend on the age and fitness of the individual, muscle fibre type and the intensity of the muscle contractions. ROS/RNS generate unique signaling cascades that are not only essential in skeletal muscle contraction and adaptation but also play a role in a wide array of cell processes including cell proliferation, protein synthesis/degradation, immune response and antioxidant defense. ROS/RNS generated by contractions are involved in a co-ordinated local response that is tightly controlled at all levels from generation to detoxification. This collection of original articles and reviews highlights investigations that measure different aspects of the redox response of skeletal muscle to aging and exercise.
540 ## - TERMS GOVERNING USE AND REPRODUCTION NOTE
Terms governing use and reproduction Creative Commons
Use and reproduction rights https://creativecommons.org/licenses/by/4.0/
Source of term cc
-- https://creativecommons.org/licenses/by/4.0/
546 ## - LANGUAGE NOTE
Language note English
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term Mitochondria
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term Sternohyoid muscle
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term uremic myopathy
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Uncontrolled term sphingomyelinase
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term Muscle Fatigue
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Uncontrolled term sirt3
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term Calveolin-3
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term NADPH Oxidase
856 40 - ELECTRONIC LOCATION AND ACCESS
Host name www.oapen.org
Uniform Resource Identifier <a href="http://journal.frontiersin.org/researchtopic/2723/redox-regulation-in-skeletal-muscle-aging-and-exercise">http://journal.frontiersin.org/researchtopic/2723/redox-regulation-in-skeletal-muscle-aging-and-exercise</a>
Access status 0
Public note DOAB: download the publication
856 40 - ELECTRONIC LOCATION AND ACCESS
Host name www.oapen.org
Uniform Resource Identifier <a href="https://directory.doabooks.org/handle/20.500.12854/57918">https://directory.doabooks.org/handle/20.500.12854/57918</a>
Access status 0
Public note DOAB: description of the publication

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