Molecular, Cellular and Model Organism Approaches for Understanding the Basis of Neurological Disease (Record no. 75794)
[ view plain ]
| 000 -LEADER | |
|---|---|
| fixed length control field | 02364naaaa2200385uu 4500 |
| 001 - CONTROL NUMBER | |
| control field | https://directory.doabooks.org/handle/20.500.12854/53863 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20220220082408.0 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 978-2-88945-173-9 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9782889451739 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.3389/978-2-88945-173-9 |
| Terms of availability | doi |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | English |
| 042 ## - AUTHENTICATION CODE | |
| Authentication code | dc |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Robert J. Harvey |
| Relationship | auth |
| 245 10 - TITLE STATEMENT | |
| Title | Molecular, Cellular and Model Organism Approaches for Understanding the Basis of Neurological Disease |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Name of publisher, distributor, etc. | Frontiers Media SA |
| Date of publication, distribution, etc. | 2017 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 1 electronic resource (183 p.) |
| 506 0# - RESTRICTIONS ON ACCESS NOTE | |
| Terms governing access | Open Access |
| Source of term | star |
| Standardized terminology for access restriction | Unrestricted online access |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | The advent of next-generation sequencing technologies has resulted in a remarkable increase our understanding of human and animal neurological disorders through the identification of disease causing or protective sequence variants. However, in many cases, robust disease models are required to understand how changes at the DNA, RNA or protein level affect neuronal and synaptic function, or key signalling pathways. In turn, these models may enable understanding of key disease processes and the identification of new targets for the medicines of the future. This e-book contains original research papers and reviews that highlight either the impact of next-generation sequencing in the understanding of neurological disorders, or utilise molecular, cellular, and whole-organism models to validate disease-causing or protective sequence variants. |
| 540 ## - TERMS GOVERNING USE AND REPRODUCTION NOTE | |
| Terms governing use and reproduction | Creative Commons |
| Use and reproduction rights | https://creativecommons.org/licenses/by/4.0/ |
| Source of term | cc |
| -- | https://creativecommons.org/licenses/by/4.0/ |
| 546 ## - LANGUAGE NOTE | |
| Language note | English |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Stem Cells |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | glycine receptor |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Amyotrophic Lateral Sclerosis |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Parkinson's disease |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | PET imaging |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | LRRK2 |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Zebrafish |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Inflammation |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | GABA-A receptor |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | NMDA receptors |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Intellectual Disability |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Kirsten Harvey |
| Relationship | auth |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Host name | www.oapen.org |
| Uniform Resource Identifier | <a href="http://journal.frontiersin.org/researchtopic/4437/molecular-cellular-and-model-organism-approaches-for-understanding-the-basis-of-neurological-disease">http://journal.frontiersin.org/researchtopic/4437/molecular-cellular-and-model-organism-approaches-for-understanding-the-basis-of-neurological-disease</a> |
| Access status | 0 |
| Public note | DOAB: download the publication |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Host name | www.oapen.org |
| Uniform Resource Identifier | <a href="https://directory.doabooks.org/handle/20.500.12854/53863">https://directory.doabooks.org/handle/20.500.12854/53863</a> |
| Access status | 0 |
| Public note | DOAB: description of the publication |
No items available.