Podocyte Pathology and Nephropathy (Record no. 76983)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02495naaaa2200337uu 4500 |
| 001 - CONTROL NUMBER | |
| control field | https://directory.doabooks.org/handle/20.500.12854/56451 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20220220085110.0 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 978-2-88919-710-1 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9782889197101 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.3389/978-2-88919-710-1 |
| Terms of availability | doi |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | English |
| 042 ## - AUTHENTICATION CODE | |
| Authentication code | dc |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Maciej Wojciech Jankowski |
| Relationship | auth |
| 245 10 - TITLE STATEMENT | |
| Title | Podocyte Pathology and Nephropathy |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Name of publisher, distributor, etc. | Frontiers Media SA |
| Date of publication, distribution, etc. | 2015 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 1 electronic resource (96 p.) |
| 506 0# - RESTRICTIONS ON ACCESS NOTE | |
| Terms governing access | Open Access |
| Source of term | star |
| Standardized terminology for access restriction | Unrestricted online access |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | The understanding of the pathogenesis of diabetic nephropathy (DN) has advanced considerably in the last few years. Much has been learned about the natural history, the relative lack of significance of microalbuminuria in reflecting underlying pathological change, questionable effects of ACEs and ARBs on the progression of nephropathy, the emergence of new biomarkers such as Cystatin and the role of cytokines, inflammatory molecules and adhesion molecules. Podocytes, the cells with limited ability to replenish and to repair, play a pivotal role in glomerular filtration. In recent years these cells have become the focus for research on pathogenesis of DN as well as other nephropathies. A recent review from the NIH has identified new insights into the pathophysiology, the genetics and the role of the podocytes and some of the important new metabolic pathways such as mTOR or autophagy which may be targeting the podocyte. Knowledge is emerging about the role of podocyte as a part of immune system and about the role of growth factors and cytokines in regulation of podocyte functions. Presented in this e-book articles highlight recent advances in our understanding of the pathogenesis of kidney pathology and the role of podocytes in this process. |
| 540 ## - TERMS GOVERNING USE AND REPRODUCTION NOTE | |
| Terms governing use and reproduction | Creative Commons |
| Use and reproduction rights | https://creativecommons.org/licenses/by/4.0/ |
| Source of term | cc |
| -- | https://creativecommons.org/licenses/by/4.0/ |
| 546 ## - LANGUAGE NOTE | |
| Language note | English |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | glomeruli |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Podocytes |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | foot processes |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | kidney disease |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Exosomes |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | diabetes |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Proteinuria |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Gavin Iain Welsh |
| Relationship | auth |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Host name | www.oapen.org |
| Uniform Resource Identifier | <a href="http://journal.frontiersin.org/researchtopic/1865/podocyte-pathology-and-nephropathy">http://journal.frontiersin.org/researchtopic/1865/podocyte-pathology-and-nephropathy</a> |
| Access status | 0 |
| Public note | DOAB: download the publication |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Host name | www.oapen.org |
| Uniform Resource Identifier | <a href="https://directory.doabooks.org/handle/20.500.12854/56451">https://directory.doabooks.org/handle/20.500.12854/56451</a> |
| Access status | 0 |
| Public note | DOAB: description of the publication |
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