Muscle-Tendon-Innervation Unit: Degeneration and Aging - Pathophysiological and Regeneration Mechanisms (Record no. 77507)

MARC details
000 -LEADER
fixed length control field 02673naaaa2200385uu 4500
001 - CONTROL NUMBER
control field https://directory.doabooks.org/handle/20.500.12854/54099
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20220220090229.0
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 978-2-88945-103-6
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9782889451036
024 7# - OTHER STANDARD IDENTIFIER
Standard number or code 10.3389/978-2-88945-103-6
Terms of availability doi
041 0# - LANGUAGE CODE
Language code of text/sound track or separate title English
042 ## - AUTHENTICATION CODE
Authentication code dc
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name Paolo Bonaldo
Relationship auth
245 10 - TITLE STATEMENT
Title Muscle-Tendon-Innervation Unit: Degeneration and Aging - Pathophysiological and Regeneration Mechanisms
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Name of publisher, distributor, etc. Frontiers Media SA
Date of publication, distribution, etc. 2017
300 ## - PHYSICAL DESCRIPTION
Extent 1 electronic resource (104 p.)
506 0# - RESTRICTIONS ON ACCESS NOTE
Terms governing access Open Access
Source of term star
Standardized terminology for access restriction Unrestricted online access
520 ## - SUMMARY, ETC.
Summary, etc. Aging is characterized by progressive deterioration of walking ability. This function loss has multiple causes including central and peripheral nerve dysfunction, loss of muscle mass and strength, as well as joints and bone alterations. Muscle-tendon unit and its innervation has a pivotal role in motor function performance that can be disrupted by overuse degeneration and aging. Research has shown that overuse degeneration and aging also share some pathophysiological mechanisms including mitochondrial dysfunction, increased apoptosis, abnormal modulation of autophagy, decline in satellite cells, increased generation of reactive oxygen species, and modification of signalling and stress response pathways. This Research Topic is intended to bring together basic researchers and clinicians working in the area of neuroscience, aging, sarcopenia and orthopaedics in human and in animal models. The aim of this cross-fertilization is to accelerate our understanding of the mechanisms involved in aging and degeneration of the muscle-tendon unit and its innervation and to explore the therapeutic potential of pharmacological and physical therapy interventions.
540 ## - TERMS GOVERNING USE AND REPRODUCTION NOTE
Terms governing use and reproduction Creative Commons
Use and reproduction rights https://creativecommons.org/licenses/by/4.0/
Source of term cc
-- https://creativecommons.org/licenses/by/4.0/
546 ## - LANGUAGE NOTE
Language note English
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term Nanoparticles
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term congenital muscular dystrophy
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term Stem/progenitor cells
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term therapy
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term Aging
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term Parkinson's camptocormia
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term Muscle
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term innervation
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term Animal Models
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term Tendon
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Cesare Faldini
Relationship auth
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Luciano Merlini
Relationship auth
856 40 - ELECTRONIC LOCATION AND ACCESS
Host name www.oapen.org
Uniform Resource Identifier <a href="http://journal.frontiersin.org/researchtopic/3777/muscle-tendon-innervation-unit-degeneration-and-aging---pathophysiological-and-regeneration-mechanis">http://journal.frontiersin.org/researchtopic/3777/muscle-tendon-innervation-unit-degeneration-and-aging---pathophysiological-and-regeneration-mechanis</a>
Access status 0
Public note DOAB: download the publication
856 40 - ELECTRONIC LOCATION AND ACCESS
Host name www.oapen.org
Uniform Resource Identifier <a href="https://directory.doabooks.org/handle/20.500.12854/54099">https://directory.doabooks.org/handle/20.500.12854/54099</a>
Access status 0
Public note DOAB: description of the publication

No items available.