Natural Products and Drug Discovery (Record no. 80415)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 06537naaaa2201705uu 4500 |
| 001 - CONTROL NUMBER | |
| control field | https://directory.doabooks.org/handle/20.500.12854/54359 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20220220100825.0 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | books978-3-03928-747-5 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9783039287468 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9783039287475 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.3390/books978-3-03928-747-5 |
| Terms of availability | doi |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | English |
| 042 ## - AUTHENTICATION CODE | |
| Authentication code | dc |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Avato, Pinarosa |
| Relationship | auth |
| 245 10 - TITLE STATEMENT | |
| Title | Natural Products and Drug Discovery |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Name of publisher, distributor, etc. | MDPI - Multidisciplinary Digital Publishing Institute |
| Date of publication, distribution, etc. | 2020 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 1 electronic resource (392 p.) |
| 506 0# - RESTRICTIONS ON ACCESS NOTE | |
| Terms governing access | Open Access |
| Source of term | star |
| Standardized terminology for access restriction | Unrestricted online access |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Natural products hold a prominent position in the current discovery and development of drugs and have diverse indications for both human and animal health. Plants, in particular, play a leading role as a source of specialized metabolites with medical effects. Other organisms, such as marine and terrestrial animals and microorganisms, produce very important drug candidate molecules. Specialized metabolites from these varied natural sources can be used directly as bioactive compounds or drug precursors. In addition, due to their broad chemical diversity, they can act as drug prototypes and/or be used as pharmacological tools for different targets. Some examples of natural metabolites that have been developed into useful medical drug are cardiotonic digoxin from Digitalis sp., antimalarial artemisinin from Artemisia annua, anti-cancer taxol from Taxus sp., or podophyllotoxin from Podophyllum peltatum, which served as a synthetic model for the anti-cancer etoposide. The study of natural products is still attracting great scientific attention and their current importance, as a valuable lead for drug discovery, is undebatable. I cordially invite authors to contribute original articles, as well as survey articles, that give the readers of Molecules **MOLECULES NEEDS TO BE ITALICIZED** updated and new perspectives on natural products in drug discovery, including but not limited to natural sources, identification and separation of bioactive phytochemicals, standardization, new biological targets, pre-clinical and clinical trials, pharmacological effects/side effects, and bioassays. |
| 540 ## - TERMS GOVERNING USE AND REPRODUCTION NOTE | |
| Terms governing use and reproduction | Creative Commons |
| Use and reproduction rights | https://creativecommons.org/licenses/by-nc-nd/4.0/ |
| Source of term | cc |
| -- | https://creativecommons.org/licenses/by-nc-nd/4.0/ |
| 546 ## - LANGUAGE NOTE | |
| Language note | English |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | dihydrochalcones |
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| Uncontrolled term | cytotoxicity-guided |
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| Uncontrolled term | n/a |
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| Uncontrolled term | harpagoside |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | biotechnology |
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| Uncontrolled term | synergy |
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| Uncontrolled term | Imperata cylindrica |
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| Uncontrolled term | 5?-dimethylchalcone (DMC) |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | antioxidant activity |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | marine resources |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | phenolic derivatives |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | secondary metabolites |
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| Uncontrolled term | antimicrobial agents |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | antimicrobial resistance |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | metabolomics |
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| Uncontrolled term | Humulus lupulus |
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| Uncontrolled term | chromatography |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | stereochemistry |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | FSE |
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| Uncontrolled term | cytokines |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | cytotoxic activity |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | glutamate |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | angiogenesis |
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| Uncontrolled term | traditional medicine |
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| Uncontrolled term | Ca2+ |
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| Uncontrolled term | L6 cell |
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| Uncontrolled term | human colon cancer cell lines |
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| Uncontrolled term | siphonous green algae |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | anti-inflammatory activity |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Phyllanthus chamacristoides |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | spectroscopic analysis |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Physcomitrella patens |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Leishmania mexicana mexicana |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | dementia |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | prenylated phenolic compounds |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | T2DM |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | HPLC-ESI-microTOF-Q-MS/MS |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Eruca sativa |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Dryopteris fragrans |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | chemosystematics |
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| Uncontrolled term | 2? |
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| Uncontrolled term | cerebellum |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Cleistocalyx operculatus |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | inflammation |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | multivariate data analysis |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Phyllanthus orbicularis |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | HPLC |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | cardiovascular disease |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Kv7 potassium channels |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | marine peptides |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | proliferation |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | sulfated coumarins |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Orobanche s.l. |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | phenylpropanoid glycosides |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Harpagophytum procumbens |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | sesquiterpenoids |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | TRPV1 |
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| Uncontrolled term | Fideloside |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | phenylethanoid glycosides |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Cuba |
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| Uncontrolled term | molecular network |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | NMR |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | ketamine |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | aging |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | GLUT4 |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | diabetes |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | oxidative stress |
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| Uncontrolled term | Lamiales |
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| Uncontrolled term | circular dichroism |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | psychosis |
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| Uncontrolled term | antinociceptive |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | immuno-regulation activity |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | terpenoids |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | NADPH oxidases |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | diabetic neuropathy |
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| Uncontrolled term | spagyric tincture |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | H2S |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | celastrol |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | isolation and quantification |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | 4?-dihydroxy-6?-methoxy-3? |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Leea indica |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | C-glycoside |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | neuropathic pain |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | PANC-1 |
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| Uncontrolled term | glucosinolates |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | flavonoids |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | bioactivities of natural products |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | cardamonin |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | isoflavones |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | terpenes |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | methicillin-resistant Staphylococcus aureus |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | malaria |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | artemisinin |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | natural products |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | devil’s claw |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | ACE inhibitory peptide |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | pPancreatic cancer |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | growth inhibitory activity |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | mass spectrometry |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | flavonoid |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | phenolics |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Astragalus boeticus L. |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | proanthocyanidins |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | opioid |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Trifolium |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Trypanosoma brucei brucei |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | acetylated astragalosides |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Fabaceae |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | bioactive peptides |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | LC-MS |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Dasycladus vermicularis |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Orobanchaceae |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | migration |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | glucoerucin |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | ESI-MS/MS |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | cancer |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | zebrafish |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | antihypertensive |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Bacopa monnieri |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | chemical derivatization |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | hypertension |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Host name | www.oapen.org |
| Uniform Resource Identifier | <a href="https://mdpi.com/books/pdfview/book/2231">https://mdpi.com/books/pdfview/book/2231</a> |
| Access status | 0 |
| Public note | DOAB: download the publication |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Host name | www.oapen.org |
| Uniform Resource Identifier | <a href="https://directory.doabooks.org/handle/20.500.12854/54359">https://directory.doabooks.org/handle/20.500.12854/54359</a> |
| Access status | 0 |
| Public note | DOAB: description of the publication |
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