Innate Immunity Programming and Memory in Resolving and Non-Resolving Inflammation (Record no. 81412)

MARC details
000 -LEADER
fixed length control field 03873naaaa2200409uu 4500
001 - CONTROL NUMBER
control field https://directory.doabooks.org/handle/20.500.12854/73734
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20220220103015.0
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 978-2-88963-582-5
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9782889635825
024 7# - OTHER STANDARD IDENTIFIER
Standard number or code 10.3389/978-2-88963-582-5
Terms of availability doi
041 0# - LANGUAGE CODE
Language code of text/sound track or separate title English
042 ## - AUTHENTICATION CODE
Authentication code dc
072 #7 - SUBJECT CATEGORY CODE
Subject category code M
Source bicssc
072 #7 - SUBJECT CATEGORY CODE
Subject category code MJCM
Source bicssc
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name Li, Liwu
Relationship edt
245 10 - TITLE STATEMENT
Title Innate Immunity Programming and Memory in Resolving and Non-Resolving Inflammation
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Name of publisher, distributor, etc. Frontiers Media SA
Date of publication, distribution, etc. 2020
300 ## - PHYSICAL DESCRIPTION
Extent 1 electronic resource (139 p.)
506 0# - RESTRICTIONS ON ACCESS NOTE
Terms governing access Open Access
Source of term star
Standardized terminology for access restriction Unrestricted online access
520 ## - SUMMARY, ETC.
Summary, etc. There is increasing evidence that suggest the presence of innate immune memory as reflected in the altered responses from programmed innate leukocyte challenged with varying natures and signal strength of inflammatory challenges. The rudimentary “memory” responses of innate leukocytes based on prior challenge histories, as well as signal strength and durations, may dramatically affect cellular and tissue homeostasis. At the translational level, innate leukocyte memory may underlie the decision making process of resolving tissue homeostasis as compared to non-resolving inflammatory diseases. Proper resolution of leukocyte homeostasis is essential for the well-being of human physiology such as proper wound repair, eradication of sporadic malignant cells, mucosal defense of infections, and tissue regeneration and growth. On the other hand, lack of inflammation resolution underlies the pathogenesis of wide ranges of acute and chronic diseases ranging from cardiovascular to neurological diseases and cancer. This series of reports will focus on this emerging topics of innate leukocyte programming dynamics and memory in health and disease. Emerging examples of leukocyte programming dynamics may include the following scenarios. First, sequential challenges with distinct inflammatory signals may alter the leukocyte expression profiles of inflammatory mediators, as exemplified by the classically trained M1 monocyte/macrophage as compared to the alternatively programmed M2 macrophages. Second, leukocytes may be adapted to unique signal strength of inflammatory challenges, as reflected in the generation of non-resolving low-grade inflammatory monocytes adapted by chronic low signals of TLR4/7 agonists. Third, the ontogeny of innate leukocytes from precursor cells as well as the life span of mature leukocytes may also be significantly impacted by the history, dosage, and duration of inflammatory signals. In light of the conceptual and translational significance of innate immune memory, this topic may cover the key aspects listed below. 1) Monocyte priming and tolerance; 2) Neutrophil priming and adaptation; 3) NK cell priming; 4) Cross-talk among innate and adaptive immune programming; 5) Innate leukocyte programming in acute and chronic inflammatory disease.
540 ## - TERMS GOVERNING USE AND REPRODUCTION NOTE
Terms governing use and reproduction Creative Commons
Use and reproduction rights https://creativecommons.org/licenses/by/4.0/
Source of term cc
-- https://creativecommons.org/licenses/by/4.0/
546 ## - LANGUAGE NOTE
Language note English
650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Medicine
Source of heading or term bicssc
650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Immunology
Source of heading or term bicssc
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term innate immune memory
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term inflammation dynamics
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term resolving and non-resolving inflammation
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term acute disease
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term chronic disease
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name McCall, Charles E.
Relationship edt
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Hu, Xiaoyu
Relationship edt
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Li, Liwu
Relationship oth
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name McCall, Charles E.
Relationship oth
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Hu, Xiaoyu
Relationship oth
856 40 - ELECTRONIC LOCATION AND ACCESS
Host name www.oapen.org
Uniform Resource Identifier <a href="https://www.frontiersin.org/research-topics/5497/innate-immunity-programming-and-memory-in-resolving-and-non-resolving-inflammation#overview">https://www.frontiersin.org/research-topics/5497/innate-immunity-programming-and-memory-in-resolving-and-non-resolving-inflammation#overview</a>
Access status 0
Public note DOAB: download the publication
856 40 - ELECTRONIC LOCATION AND ACCESS
Host name www.oapen.org
Uniform Resource Identifier <a href="https://directory.doabooks.org/handle/20.500.12854/73734">https://directory.doabooks.org/handle/20.500.12854/73734</a>
Access status 0
Public note DOAB: description of the publication

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