Malignant Mesothelioma (Record no. 81743)

MARC details
000 -LEADER
fixed length control field 05130naaaa2201249uu 4500
001 - CONTROL NUMBER
control field https://directory.doabooks.org/handle/20.500.12854/77046
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20220220103722.0
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number books978-3-0365-2367-5
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9783036523682
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9783036523675
024 7# - OTHER STANDARD IDENTIFIER
Standard number or code 10.3390/books978-3-0365-2367-5
Terms of availability doi
041 0# - LANGUAGE CODE
Language code of text/sound track or separate title English
042 ## - AUTHENTICATION CODE
Authentication code dc
072 #7 - SUBJECT CATEGORY CODE
Subject category code M
Source bicssc
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name L. Pouliquen, Daniel
Relationship edt
245 10 - TITLE STATEMENT
Title Malignant Mesothelioma
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Basel, Switzerland
Name of publisher, distributor, etc. MDPI - Multidisciplinary Digital Publishing Institute
Date of publication, distribution, etc. 2021
300 ## - PHYSICAL DESCRIPTION
Extent 1 electronic resource (328 p.)
506 0# - RESTRICTIONS ON ACCESS NOTE
Terms governing access Open Access
Source of term star
Standardized terminology for access restriction Unrestricted online access
520 ## - SUMMARY, ETC.
Summary, etc. Malignant mesothelioma (MM) is a rare and aggressive cancer, related to chronic inflammation and oxidative stress caused mainly by exposure to asbestos. Although this mineral has been banned for decades in many countries, epidemiologists predict the MM epidemic will last past 2040, raising many concerns in public health given its late diagnosis, dismal prognosis, and lack of current efficient therapies.To deal with this situation, important breakthroughs have recently been made in the understanding of MM’s complex biology and the carcinogenic process of the different patterns of the disease. Examples of these include the development of new biomarkers and the deciphering of gene–environment interactions, molecular mechanisms of invasiveness, deregulated pathways, altered expression of miRNAs, DNA damage repair, or metabolic profile. From now on, MM’s aggressive and chemoresistant character appears linked to a polyclonal malignancy, and heterogeneity in molecular alterations.Given these improvements, new therapeutic targets are being explored to solve the double challenge faced by clinicians. The first is to reduce tumor development and its wasting consequences as soon as possible, without resistance and with limited toxicity. The second is to stimulate the recognition of tumor cells by the induction of a specific immune response. This Special Issue will highlight all these aspects.
540 ## - TERMS GOVERNING USE AND REPRODUCTION NOTE
Terms governing use and reproduction Creative Commons
Use and reproduction rights https://creativecommons.org/licenses/by/4.0/
Source of term cc
-- https://creativecommons.org/licenses/by/4.0/
546 ## - LANGUAGE NOTE
Language note English
650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Medicine
Source of heading or term bicssc
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Uncontrolled term well-differentiated papillary mesothelioma
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Uncontrolled term WDPM
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Uncontrolled term malignant mesothelioma
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Uncontrolled term DNA sequencing
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Uncontrolled term mutation
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Uncontrolled term mesothelioma
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Uncontrolled term tumor suppressor
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Uncontrolled term targeted therapy
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Uncontrolled term immunotherapy
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Uncontrolled term biomarkers
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Uncontrolled term proteomics
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Uncontrolled term macrophage-capping protein
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Uncontrolled term fatty acid-binding protein
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Uncontrolled term laminin subunit beta-2
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Uncontrolled term selenium-binding protein 1
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Uncontrolled term carcinogenesis
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Uncontrolled term malignant pleural mesothelioma
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Uncontrolled term asbestos exposure
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Uncontrolled term DNA methylation
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Uncontrolled term lymphocyte-to-monocyte ratio
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Uncontrolled term inflammation
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Uncontrolled term infiltrating immune cells
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Uncontrolled term immune therapy
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Uncontrolled term VATS
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Uncontrolled term extrapleural pneumonectomy
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Uncontrolled term pleurectomy decortication
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Uncontrolled term FDG
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Uncontrolled term PET-CT
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Uncontrolled term mesothelium
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Uncontrolled term oxidative stress
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Uncontrolled term redox-sensitive factors
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Uncontrolled term asbestos
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Uncontrolled term carbon nanotubes
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Uncontrolled term protein-protein interactions
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Uncontrolled term systems biology
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Uncontrolled term network analysis
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Uncontrolled term drug repurposing
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Uncontrolled term pleural mesothelioma
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Uncontrolled term gene expression
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Uncontrolled term immunogenicity
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Uncontrolled term sarcomatoid
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Uncontrolled term MPM
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Uncontrolled term lurbinectedin
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Uncontrolled term DNA damage response
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Uncontrolled term histotype
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Uncontrolled term Hippo pathway
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Uncontrolled term NF2
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Uncontrolled term BAP1
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Uncontrolled term CDKN2A
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Uncontrolled term PTCH1
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Uncontrolled term SETD2
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Uncontrolled term MTAP
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Uncontrolled term liquid biopsies
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Uncontrolled term circulating tumor DNA
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Uncontrolled term plasma
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Uncontrolled term cancer-specific mutations
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Uncontrolled term tumor microenvironment
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Uncontrolled term tumor-associated macrophages
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Uncontrolled term immunohistochemistry
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Uncontrolled term interaction analysis
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Uncontrolled term pleural effusion
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Uncontrolled term n/a
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Kopecka, Joanna
Relationship edt
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name L. Pouliquen, Daniel
Relationship oth
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Kopecka, Joanna
Relationship oth
856 40 - ELECTRONIC LOCATION AND ACCESS
Host name www.oapen.org
Uniform Resource Identifier <a href="https://mdpi.com/books/pdfview/book/4656">https://mdpi.com/books/pdfview/book/4656</a>
Access status 0
Public note DOAB: download the publication
856 40 - ELECTRONIC LOCATION AND ACCESS
Host name www.oapen.org
Uniform Resource Identifier <a href="https://directory.doabooks.org/handle/20.500.12854/77046">https://directory.doabooks.org/handle/20.500.12854/77046</a>
Access status 0
Public note DOAB: description of the publication

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