Malignant Mesothelioma (Record no. 81743)
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                            | 000 -LEADER | |
|---|---|
| fixed length control field | 05130naaaa2201249uu 4500 | 
| 001 - CONTROL NUMBER | |
| control field | https://directory.doabooks.org/handle/20.500.12854/77046 | 
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20220220103722.0 | 
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | books978-3-0365-2367-5 | 
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9783036523682 | 
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9783036523675 | 
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.3390/books978-3-0365-2367-5 | 
| Terms of availability | doi | 
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | English | 
| 042 ## - AUTHENTICATION CODE | |
| Authentication code | dc | 
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | M | 
| Source | bicssc | 
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | L. Pouliquen, Daniel | 
| Relationship | edt | 
| 245 10 - TITLE STATEMENT | |
| Title | Malignant Mesothelioma | 
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Basel, Switzerland | 
| Name of publisher, distributor, etc. | MDPI - Multidisciplinary Digital Publishing Institute | 
| Date of publication, distribution, etc. | 2021 | 
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 1 electronic resource (328 p.) | 
| 506 0# - RESTRICTIONS ON ACCESS NOTE | |
| Terms governing access | Open Access | 
| Source of term | star | 
| Standardized terminology for access restriction | Unrestricted online access | 
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Malignant mesothelioma (MM) is a rare and aggressive cancer, related to chronic inflammation and oxidative stress caused mainly by exposure to asbestos. Although this mineral has been banned for decades in many countries, epidemiologists predict the MM epidemic will last past 2040, raising many concerns in public health given its late diagnosis, dismal prognosis, and lack of current efficient therapies.To deal with this situation, important breakthroughs have recently been made in the understanding of MM’s complex biology and the carcinogenic process of the different patterns of the disease. Examples of these include the development of new biomarkers and the deciphering of gene–environment interactions, molecular mechanisms of invasiveness, deregulated pathways, altered expression of miRNAs, DNA damage repair, or metabolic profile. From now on, MM’s aggressive and chemoresistant character appears linked to a polyclonal malignancy, and heterogeneity in molecular alterations.Given these improvements, new therapeutic targets are being explored to solve the double challenge faced by clinicians. The first is to reduce tumor development and its wasting consequences as soon as possible, without resistance and with limited toxicity. The second is to stimulate the recognition of tumor cells by the induction of a specific immune response. This Special Issue will highlight all these aspects. | 
| 540 ## - TERMS GOVERNING USE AND REPRODUCTION NOTE | |
| Terms governing use and reproduction | Creative Commons | 
| Use and reproduction rights | https://creativecommons.org/licenses/by/4.0/ | 
| Source of term | cc | 
| -- | https://creativecommons.org/licenses/by/4.0/ | 
| 546 ## - LANGUAGE NOTE | |
| Language note | English | 
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Medicine | 
| Source of heading or term | bicssc | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | well-differentiated papillary mesothelioma | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | WDPM | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | malignant mesothelioma | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | DNA sequencing | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | mutation | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | mesothelioma | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | tumor suppressor | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | targeted therapy | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | immunotherapy | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | biomarkers | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | proteomics | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | macrophage-capping protein | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | fatty acid-binding protein | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | laminin subunit beta-2 | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | selenium-binding protein 1 | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | carcinogenesis | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | malignant pleural mesothelioma | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | asbestos exposure | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | DNA methylation | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | lymphocyte-to-monocyte ratio | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | epigenome-wide analysis | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | survival analysis | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | metabolomics | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | radiotherapy | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | cancers | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | inflammation | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | infiltrating immune cells | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | prognostic biomarker | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | predictive biomarker | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | immune therapy | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | VATS | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | extrapleural pneumonectomy | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | pleurectomy decortication | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | therapy response | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | survival | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | FDG | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | PET-CT | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | mesothelium | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | oxidative stress | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | redox-sensitive factors | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | asbestos | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | carbon nanotubes | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | protein-protein interactions | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | systems biology | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | network analysis | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | drug repurposing | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | pleural mesothelioma | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | gene expression | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | immunogenicity | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | sarcomatoid | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | epithelioid | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | first line | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | meta-analysis | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | systematic review | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | MPM | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | lurbinectedin | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | DNA damage response | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | histotype | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Hippo pathway | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | NF2 | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | BAP1 | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | CDKN2A | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | PTCH1 | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | SETD2 | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | MTAP | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | liquid biopsies | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | circulating tumor DNA | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | plasma | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | cancer-specific mutations | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | genomics | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | cancer biomarkers | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | tumor microenvironment | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | tumor-associated macrophages | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | dendritic cells | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | immunohistochemistry | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | interaction analysis | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | pleural effusion | 
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | n/a | 
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Kopecka, Joanna | 
| Relationship | edt | 
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | L. Pouliquen, Daniel | 
| Relationship | oth | 
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Kopecka, Joanna | 
| Relationship | oth | 
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Host name | www.oapen.org | 
| Uniform Resource Identifier | <a href="https://mdpi.com/books/pdfview/book/4656">https://mdpi.com/books/pdfview/book/4656</a> | 
| Access status | 0 | 
| Public note | DOAB: download the publication | 
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Host name | www.oapen.org | 
| Uniform Resource Identifier | <a href="https://directory.doabooks.org/handle/20.500.12854/77046">https://directory.doabooks.org/handle/20.500.12854/77046</a> | 
| Access status | 0 | 
| Public note | DOAB: description of the publication | 
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