Charged Particles in Oncology (Record no. 81847)

MARC details
000 -LEADER
fixed length control field 03400naaaa2200385uu 4500
001 - CONTROL NUMBER
control field https://directory.doabooks.org/handle/20.500.12854/43025
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20220220103917.0
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 978-2-88945-391-7
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9782889453917
024 7# - OTHER STANDARD IDENTIFIER
Standard number or code 10.3389/978-2-88945-391-7
Terms of availability doi
041 0# - LANGUAGE CODE
Language code of text/sound track or separate title English
042 ## - AUTHENTICATION CODE
Authentication code dc
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name Marco Durante
Relationship auth
245 10 - TITLE STATEMENT
Title Charged Particles in Oncology
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Name of publisher, distributor, etc. Frontiers Media SA
Date of publication, distribution, etc. 2018
300 ## - PHYSICAL DESCRIPTION
Extent 1 electronic resource (650 p.)
506 0# - RESTRICTIONS ON ACCESS NOTE
Terms governing access Open Access
Source of term star
Standardized terminology for access restriction Unrestricted online access
520 ## - SUMMARY, ETC.
Summary, etc. High-energy charged particles represent a cutting-edge technique in radiation oncology. Protons and carbon ions are used in several centers all over the world for the treatment of different solid tumors. Typical indications are ocular malignancies, tumors of the base of the skull, hepatocellular carcinomas and various sarcomas. The physical characteristics of the charged particles (Bragg peak) allow sparing of much more normal tissues than it is possible using conventional X-rays, and for this reason all pediatric tumors are considered eligible for protontherapy. Ions heavier than protons also display special radiobiological characteristics, which make them effective against radioresistant and hypoxic tumors. On the other hand, protons and ions with high charge (Z) and energy (HZE particles) represent a major risk for human space exploration. The main late effect of radiation exposure is cancer induction, and at the moment the dose limits for astronauts are based on cancer mortality risk. The Mars Science Laboratory (MSL) measured the dose on the route to Mars and on the planet’s surface, suggesting that a human exploration missions will exceed the radiation risk limits. Notwithstanding many studies on carcinogenesis induced by protons and heavy ions, the risk uncertainty remains very high. In this research topic we aim at gathering the experiences and opinions of scientists dealing with high-energy charged particles either for cancer treatment or for space radiation protection. Clinical results with protons and heavy ions, as well as research in medical physics and pre-clinical radiobiology are reported. In addition, ground-based and spaceflight studies on the effects of space radiation are included in this book. Particularly relevant for space studies are the clinical results on normal tissue complications and second cancers. The eBook nicely demonstrates that particle therapy in oncology and protection of astronauts from space radiation share many common topics, and can learn from each other.
540 ## - TERMS GOVERNING USE AND REPRODUCTION NOTE
Terms governing use and reproduction Creative Commons
Use and reproduction rights https://creativecommons.org/licenses/by/4.0/
Source of term cc
-- https://creativecommons.org/licenses/by/4.0/
546 ## - LANGUAGE NOTE
Language note English
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term carbon ions
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term heavy ions
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term Mars
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term proton therapy
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Uncontrolled term radiotherapy
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term particle radiobiology
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term protons
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term space radiation protection
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term Charged particles
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term space travel
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Francis A. Cucinotta
Relationship auth
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Jay S. Loeffler
Relationship auth
856 40 - ELECTRONIC LOCATION AND ACCESS
Host name www.oapen.org
Uniform Resource Identifier <a href="https://www.frontiersin.org/research-topics/3520/charged-particles-in-oncology">https://www.frontiersin.org/research-topics/3520/charged-particles-in-oncology</a>
Access status 0
Public note DOAB: download the publication
856 40 - ELECTRONIC LOCATION AND ACCESS
Host name www.oapen.org
Uniform Resource Identifier <a href="https://directory.doabooks.org/handle/20.500.12854/43025">https://directory.doabooks.org/handle/20.500.12854/43025</a>
Access status 0
Public note DOAB: description of the publication

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