Sensory Hair Cell Death and Regeneration (Record no. 81944)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03077naaaa2200385uu 4500 |
| 001 - CONTROL NUMBER | |
| control field | https://directory.doabooks.org/handle/20.500.12854/59232 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20220220104137.0 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 978-2-88945-000-8 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9782889450008 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.3389/978-2-88945-000-8 |
| Terms of availability | doi |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | English |
| 042 ## - AUTHENTICATION CODE | |
| Authentication code | dc |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Michael E. Smith |
| Relationship | auth |
| 245 10 - TITLE STATEMENT | |
| Title | Sensory Hair Cell Death and Regeneration |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Name of publisher, distributor, etc. | Frontiers Media SA |
| Date of publication, distribution, etc. | 2016 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 1 electronic resource (266 p.) |
| 506 0# - RESTRICTIONS ON ACCESS NOTE | |
| Terms governing access | Open Access |
| Source of term | star |
| Standardized terminology for access restriction | Unrestricted online access |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Sensory hair cells are the specialized mechanosensory receptors found in vertebrate auditory, vestibular, and lateral line organs that transduce vibratory and acoustic stimuli into the sensations of hearing and balance. Hair cells can be damaged due to such factors as aging, ototoxic chemicals, acoustic trauma, infection, or genetic factors. Loss of these hair cells lead to deficits in hearing and balance, and in mammals, such deficits are permanent. In contrast, non-mammalian vertebrates exhibit the capability to regenerate missing hair cells. Researchers have been examining the process of hair cell death and regeneration in animal models in an attempt to find ways of either preventing hair cell loss or stimulating the production of new hair cells in mammals, with the ultimate goal of finding new therapeutics for human sensorineural hearing and balance deficits. This has led to a wide array of research on sensory hair cells- such as understanding the factors that cause hair cell loss and finding agents that protect them from damage, elucidating the cell signaling pathways activated during hair cell death, examining the genes and cellular pathways that are regulated during the process of hair cell death and regeneration, and characterizing the functional sensory loss and recovery following acoustic or ototoxic insults to the inner ear. This research has involved cell and developmental biologists, physiologists, geneticists, bioinformaticians, and otolaryngologists. In this Research Topic, we have collated reviews of the past progress of hair cell death and regeneration studies and original research articles advancing sensory hair cell death and regeneration research into the future. |
| 540 ## - TERMS GOVERNING USE AND REPRODUCTION NOTE | |
| Terms governing use and reproduction | Creative Commons |
| Use and reproduction rights | https://creativecommons.org/licenses/by/4.0/ |
| Source of term | cc |
| -- | https://creativecommons.org/licenses/by/4.0/ |
| 546 ## - LANGUAGE NOTE | |
| Language note | English |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Regeneration |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Neuromast |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | ototoxicity |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Hair cells |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | auditory |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Cell Death |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Cochlea |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Otoprotection |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Otic development |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Hearing Loss |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Allison B. Coffin |
| Relationship | auth |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Andrew K. Groves |
| Relationship | auth |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Host name | www.oapen.org |
| Uniform Resource Identifier | <a href="http://journal.frontiersin.org/researchtopic/2730/sensory-hair-cell-death-and-regeneration">http://journal.frontiersin.org/researchtopic/2730/sensory-hair-cell-death-and-regeneration</a> |
| Access status | 0 |
| Public note | DOAB: download the publication |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Host name | www.oapen.org |
| Uniform Resource Identifier | <a href="https://directory.doabooks.org/handle/20.500.12854/59232">https://directory.doabooks.org/handle/20.500.12854/59232</a> |
| Access status | 0 |
| Public note | DOAB: description of the publication |
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