Novel clinical applications of extracellular vesicles (Record no. 82149)

MARC details
000 -LEADER
fixed length control field 03289naaaa2200385uu 4500
001 - CONTROL NUMBER
control field https://directory.doabooks.org/handle/20.500.12854/54870
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20220220104600.0
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 978-2-88919-645-6
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9782889196456
024 7# - OTHER STANDARD IDENTIFIER
Standard number or code 10.3389/978-2-88919-645-6
Terms of availability doi
041 0# - LANGUAGE CODE
Language code of text/sound track or separate title English
042 ## - AUTHENTICATION CODE
Authentication code dc
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name Matias Saenz-Cuesta
Relationship auth
245 10 - TITLE STATEMENT
Title Novel clinical applications of extracellular vesicles
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Name of publisher, distributor, etc. Frontiers Media SA
Date of publication, distribution, etc. 2015
300 ## - PHYSICAL DESCRIPTION
Extent 1 electronic resource (66 p.)
506 0# - RESTRICTIONS ON ACCESS NOTE
Terms governing access Open Access
Source of term star
Standardized terminology for access restriction Unrestricted online access
520 ## - SUMMARY, ETC.
Summary, etc. During the last years, the research on extracellular vesicles (EVs) has raised giving new insights into pathophysiology of several diseases. EVs are membrane-bound particles secreted by almost all cell types. Depending on their biogenesis and size they include exosomes, microparticles / microvesicles and apoptotic bodies. Characteristically, EVs carry markers from the source cell membrane and contain genetic material, lipids and proteins inside. They are known to play a role in cell-to-cell communication and to produce genotypic and phenotypic modifications in the target cell including: antigen presentation, apoptosis induction, cellular activation, inhibition or differentiation. In particular, increasing concentrations of EVs have been found in many diseases such as cancer, autoimmune and cardiovascular diseases, among others. Most of the studies in EVs are focused on the characterization of EVs compounds, identifying mechanism of action, their potential use as biomarkers, and few of them investigate a therapeutic usage. However, there are some issues to be achieved on the path to their clinical application. This research topic offers a common place to discuss current and novel clinical applications of EVs pointing on future directions. We encouraged the submission of original articles, reviews, hypothesis, controversies, future perspectives and personal viewpoints on the following topics of interest, but not limited to: • Contribution of EVs to better understand the pathology of immunological diseases. • Standardization of isolation and quantification protocols in the daily clinical practice. • Possible applications of EVs as clinical biomarkers (diagnostic, prognostic and evolution marker). • Therapeutic role of EVs being vehicles of specific cargo: current clinical trials? • Novel immunological functions of EVs.
540 ## - TERMS GOVERNING USE AND REPRODUCTION NOTE
Terms governing use and reproduction Creative Commons
Use and reproduction rights https://creativecommons.org/licenses/by/4.0/
Source of term cc
-- https://creativecommons.org/licenses/by/4.0/
546 ## - LANGUAGE NOTE
Language note English
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term clinical application
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Uncontrolled term extracellular vesicles
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term biomarkers
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Uncontrolled term Immunotherapy
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Uncontrolled term microparticles
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Uncontrolled term omics-technologies
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Uncontrolled term protocol standardization
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Uncontrolled term Exosomes
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Uncontrolled term microvescicles
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term Cancer
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name David Otaegui
Relationship auth
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Maria Mittelbrunn
Relationship auth
856 40 - ELECTRONIC LOCATION AND ACCESS
Host name www.oapen.org
Uniform Resource Identifier <a href="http://journal.frontiersin.org/researchtopic/2517/novel-clinical-applications-of-extracellular-vesicles">http://journal.frontiersin.org/researchtopic/2517/novel-clinical-applications-of-extracellular-vesicles</a>
Access status 0
Public note DOAB: download the publication
856 40 - ELECTRONIC LOCATION AND ACCESS
Host name www.oapen.org
Uniform Resource Identifier <a href="https://directory.doabooks.org/handle/20.500.12854/54870">https://directory.doabooks.org/handle/20.500.12854/54870</a>
Access status 0
Public note DOAB: description of the publication

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