Musarò, Antonio <br/><br/>
Muscle Homeostasis and Regeneration : From Molecular Mechanisms to Therapeutic Opportunities 

 - Basel, Switzerland  MDPI - Multidisciplinary Digital Publishing Institute  2020 
 - 1 electronic resource (500 p.) 
<br/><br/> Open Access 
<br/><br/> The book is a collection of original research and review articles addressing the intriguing field of the cellular and molecular players involved in muscle homeostasis and regeneration. One of the most ambitious aspirations of modern medical science is the possibility of regenerating any damaged part of the body, including skeletal muscle. This desire has prompted clinicians and researchers to search for innovative technologies aimed at replacing organs and tissues that are compromised. In this context, the papers, collected in this book, addressing a specific aspects of muscle homeostasis and regeneration under physiopathologic conditions, will help us to better understand the underlying mechanisms of muscle healing and will help to design more appropriate therapeutic approaches to improve muscle regeneration and to counteract muscle diseases. 
<br/><br/><br/>Creative Commons 
<br/><br/><br/>English 
<br/><br/><label>ISBN: </label>books978-3-03943-437-4 9783039434367 9783039434374 
<br/><br/><label>Standard No.: </label>10.3390/books978-3-03943-437-4  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Research & information: general<br/>Biology, life sciences
<br/><br/><label>Subjects--Index Terms: </label>lysine mTORC1 satellite cells proliferation skeletal muscle growth muscle satellite cell transthyretin thyroid hormone myogenesis exosomes skeletal muscle genotype genetic variation muscle phenotypes sarcopenia aging calcium homeostasis hibernation mitochondria sarcoplasmic reticulum Acvr1b Tgfbr1 myostatin Col1a1 fibrosis atrophy IGF2R muscle homeostasis inflammation muscular dystrophy pericytes macrophages Nfix phagocytosis RhoA-ROCK1 splicing isoforms CRISPR-Cas9 exon deletion NF-Y muscle differentiation C2C12 cells denervation neuromuscular junction heavy resistance exercise acetylcholine receptor cell culture neonatal myosin neural cell adhesion molecule biomarkers mitophagy mitochondrial dynamics mitochondrial quality control mitochondrial-derived vesicles (MDVs) mitochondrial-lysosomal axis Hibernation electron microscopy immunocytochemistry α-smooth muscle actin confocal microscopy connexin 43 connexin 26 gap junctions myofibroblasts Platelet-Rich Plasma transforming growth factor (TGF)-β1 muscle regeneration inflammatory response cell precursors experimental methods stem cell markers muscles heterotopic ossification skeletal muscle stem and progenitor cells HO precursors muscle atrophy septicemia mitochondrial fusion mitochondrial fission iPSC extracellular vesicles Drosophila muscle genetic control muscle diversification fascicle myofiber myofibril sarcomere hypertrophy hyperplasia splitting radial growth longitudinal growth exercise muscle stem cells stem cells niche neuromuscular disorders Duchenne muscular dystrophy pharmacological approach single-cell mass cytometry skeletal muscle regeneration skeletal muscle homeostasis fibro/adipogenic progenitors myogenic progenitors muscle populations evolution metazoans differentiation transdifferentiation muscle precursors regenerative medicine stem cells FAPs tissue niche growth factors muscle pathology