TY - GEN AU - Musarò,Antonio AU - Musarò,Antonio TI - Muscle Homeostasis and Regeneration : From Molecular Mechanisms to Therapeutic Opportunities SN - books978-3-03943-437-4 PY - 2020/// CY - Basel, Switzerland PB - MDPI - Multidisciplinary Digital Publishing Institute KW - Research & information: general KW - bicssc KW - Biology, life sciences KW - lysine KW - mTORC1 KW - satellite cells KW - proliferation KW - skeletal muscle growth KW - muscle satellite cell KW - transthyretin KW - thyroid hormone KW - myogenesis KW - exosomes KW - skeletal muscle KW - genotype KW - genetic variation KW - muscle phenotypes KW - sarcopenia KW - aging KW - calcium homeostasis KW - hibernation KW - mitochondria KW - sarcoplasmic reticulum KW - Acvr1b KW - Tgfbr1 KW - myostatin KW - Col1a1 KW - fibrosis KW - atrophy KW - IGF2R KW - muscle homeostasis KW - inflammation KW - muscular dystrophy KW - pericytes KW - macrophages KW - Nfix KW - phagocytosis KW - RhoA-ROCK1 KW - splicing isoforms KW - CRISPR-Cas9 KW - exon deletion KW - NF-Y KW - muscle differentiation KW - C2C12 cells KW - denervation KW - neuromuscular junction KW - heavy resistance exercise KW - acetylcholine receptor KW - cell culture KW - neonatal myosin KW - neural cell adhesion molecule KW - biomarkers KW - mitophagy KW - mitochondrial dynamics KW - mitochondrial quality control KW - mitochondrial-derived vesicles (MDVs) KW - mitochondrial-lysosomal axis KW - Hibernation KW - electron microscopy KW - immunocytochemistry KW - α-smooth muscle actin KW - confocal microscopy KW - connexin 43 KW - connexin 26 KW - gap junctions KW - myofibroblasts KW - Platelet-Rich Plasma KW - transforming growth factor (TGF)-β1 KW - muscle regeneration KW - inflammatory response KW - cell precursors KW - experimental methods KW - stem cell markers KW - muscles KW - heterotopic ossification KW - skeletal muscle stem and progenitor cells KW - HO precursors KW - muscle atrophy KW - septicemia KW - mitochondrial fusion KW - mitochondrial fission KW - iPSC KW - extracellular vesicles KW - Drosophila KW - muscle KW - genetic control KW - muscle diversification KW - fascicle KW - myofiber KW - myofibril KW - sarcomere KW - hypertrophy KW - hyperplasia KW - splitting KW - radial growth KW - longitudinal growth KW - exercise KW - muscle stem cells KW - stem cells niche KW - neuromuscular disorders KW - Duchenne muscular dystrophy KW - pharmacological approach KW - single-cell KW - mass cytometry KW - skeletal muscle regeneration KW - skeletal muscle homeostasis KW - fibro/adipogenic progenitors KW - myogenic progenitors KW - muscle populations KW - evolution KW - metazoans KW - differentiation KW - transdifferentiation KW - muscle precursors KW - regenerative medicine KW - stem cells KW - FAPs KW - tissue niche KW - growth factors KW - muscle pathology N1 - Open Access N2 - The book is a collection of original research and review articles addressing the intriguing field of the cellular and molecular players involved in muscle homeostasis and regeneration. One of the most ambitious aspirations of modern medical science is the possibility of regenerating any damaged part of the body, including skeletal muscle. This desire has prompted clinicians and researchers to search for innovative technologies aimed at replacing organs and tissues that are compromised. In this context, the papers, collected in this book, addressing a specific aspects of muscle homeostasis and regeneration under physiopathologic conditions, will help us to better understand the underlying mechanisms of muscle healing and will help to design more appropriate therapeutic approaches to improve muscle regeneration and to counteract muscle diseases UR - https://mdpi.com/books/pdfview/book/3108 UR - https://directory.doabooks.org/handle/20.500.12854/69316 ER -