Barceló-Coblijn, Gwendolyn <br/><br/>
The Interplay of Microbiome and Immune Response in Health and Diseases 

 -  MDPI - Multidisciplinary Digital Publishing Institute  2019 
 - 1 electronic resource (206 p.) 
<br/><br/> Open Access 
<br/><br/> [Increasing evidence suggests that microbiota and especially the gut microbiota (the microbes inhabiting the gut including bacteria, archaea, viruses, and fungi) plays a key role in human physiology and pathology. Recent findings indicate how dysbiosis—an imbalance in the composition and organization of microbial populations—could severely impact the development of different medical conditions (from metabolic to mood disorders), providing new insights into the comprehension of diverse diseases, such as IBD, obesity, asthma, autism, stroke, diabetes, and cancer. Given that microbial cells in the gut outnumber host cells, microbiota influences human physiology both functionally and structurally. Microbial metabolites bridge various—even distant—areas of the organism by way of the immune and hormone system. For instance, it is now clear that the mutual interaction between the gastrointestinal tract and the brain (gut–brain axis), often involves gut microbiota, indicating that the crosstalk between the organism and its microbial residents represents a fundamental aspect of both the establishment and maintenance of healthy conditions. Moreover, it is crucial to recognize that beyond the intestinal tract, microbiota populates other host organs and tissues (e.g., skin and oral mucosa). We have edited this eBook with the aim of publishing manuscripts focusing on the impact of microbiota in the development of different diseases and their associated treatments.] 
<br/><br/><br/>Creative Commons 
<br/><br/><br/>English 
<br/><br/><label>ISBN: </label>books978-3-03921-647-5 9783039216475 9783039216468 
<br/><br/><label>Standard No.: </label>10.3390/books978-3-03921-647-5  doi 
<br/><br/><label>Subjects--Index Terms: </label>gastrointestinal diseases sterile inflammation n/a Staphylococcus spp. etiopathogenesis colitis Escherichia coli bacteriophages atopic dermatitis intravenous immunoglobulin G adaptive immunity 16S rRNA gene vaginal microbiota modularity innate immunity gut-liver axis disease activity immune system cytokines commensals Staphylococcus aureus dysbiosis fecal transplantation TLR mimicry etanercept dextran sulfate sodium CAR T-cell 3-dihydroxy-4-methoxyBenzaldehyde chemo free treatment Staphylococcus epidermis rheumatoid arthritis microbiome co-occurrence network immune epigenetics 2 autoimmunity superoxide dismutase precision medicine metabolism adoptive cell transfer (ACT) gut barrier antibiotics checkpoint inhibitors probiotics microbiota Candida albicans Enterococcus faecalis chronic liver diseases TCR anaerobic bacteria HSV2 bacteriocins methotrexate microbial interactions T cells virus mice lymphoid malignancies HPV macrophages anti-TNF-? inflammation chondroitin sulfate disaccharide immunotherapy genomics immuno-oncology diet aerobic bacteria immunological niche melanin health chemokines gut microbiota cutaneous immunity HIV TIL cancer global network