TY  - GEN
AU  - Joseph C.Sun
AU  - Marco Colonna
AU  - Chiara Romagnani
TI  - The Second Life of Natural Killer (NK) Cells
SN  - 978-2-88945-546-1
PY  - 2018///
PB  - Frontiers Media SA
KW  - natural killer cells
KW  - ILC
KW  - NK cells
KW  - immune therapy
KW  - viral infection
KW  - NK cell education
KW  - immunotherapy
KW  - MHC-I
KW  - cancer
KW  - immune regulation
KW  - adaptive immunity
N1  - Open Access
N2  - Natural Killer (NK) cells are innate lymphocytes, now recognized as members of a larger family of “Innate lymphoid cells” (ILCs). Both murine and human NK cells are well characterized effector cells with cytotoxic as well as cytokine production ability which mainly react in response to microbial and cell stress stimuli, thus playing a central role in the defense against pathogen infection, in tumor surveillance and in regulating immune homeostasis. Despite these established concepts, our understanding of the complexity of NK cells, also in view of their developmental and functional relationship with other ILC subsets, is only recently emerging. This Research Topic highlights the recent advances in NK cell (and ILC) research in human and mouse from basic research to clinical applications
UR  - https://www.frontiersin.org/research-topics/4053/the-second-life-of-natural-killer-nk-cells
UR  - https://directory.doabooks.org/handle/20.500.12854/59076
ER  -