James Shorter <br/><br/>
The Role of AAA+ Proteins in Protein Repair and Degradation 

 -  Frontiers Media SA  2018 
 - 1 electronic resource (287 p.) 
<br/><br/> Open Access 
<br/><br/> ATPases Associated with diverse cellular Activities (AAA+) comprise a superfamily of proteins that are defined by the presence of the AAA+ domain containing canonical Walker A and B motifs required for ATP binding and hydrolysis. Members of this superfamily act on other proteins, DNA, RNA, or multicomponent complexes to affect their conformation or their assembly. There have been substantial advances in understanding the structure and mechanism of function of a large number of AAA+ proteins. In this Research Topic, review articles and original research papers discuss new aspects as well as provide a detailed overview of several AAA+ proteins, namely: ClpXP, Lon, ClpB, Hsp104, p97, AAA+ proteins of the proteasome, Rubisco activases, Torsin, Pontin, and Reptin. 
<br/><br/><br/>Creative Commons 
<br/><br/><br/>English 
<br/><br/><label>ISBN: </label>978-2-88945-656-7 9782889456567 
<br/><br/><label>Standard No.: </label>10.3389/978-2-88945-656-7  doi 
<br/><br/><label>Subjects--Index Terms: </label>ATPases Associated with diverse cellular Activities Hsp104 Torsin Pontin Lon Rubisco activase ClpXP Reptin p97 Proteasome