TY  - GEN
AU  - James Shorter
AU  - Walid A.Houry
TI  - The Role of AAA+ Proteins in Protein Repair and Degradation
SN  - 978-2-88945-656-7
PY  - 2018///
PB  - Frontiers Media SA
KW  - ATPases Associated with diverse cellular Activities
KW  - Hsp104
KW  - Torsin
KW  - Pontin
KW  - Lon
KW  - Rubisco activase
KW  - ClpXP
KW  - Reptin
KW  - p97
KW  - Proteasome
N1  - Open Access
N2  - ATPases Associated with diverse cellular Activities (AAA+) comprise a superfamily of proteins that are defined by the presence of the AAA+ domain containing canonical Walker A and B motifs required for ATP binding and hydrolysis. Members of this superfamily act on other proteins, DNA, RNA, or multicomponent complexes to affect their conformation or their assembly. There have been substantial advances in understanding the structure and mechanism of function of a large number of AAA+ proteins. In this Research Topic, review articles and original research papers discuss new aspects as well as provide a detailed overview of several AAA+ proteins, namely: ClpXP, Lon, ClpB, Hsp104, p97, AAA+ proteins of the proteasome, Rubisco activases, Torsin, Pontin, and Reptin
UR  - https://www.frontiersin.org/research-topics/4803/the-role-of-aaa-proteins-in-protein-repair-and-degradation
UR  - https://directory.doabooks.org/handle/20.500.12854/58574
ER  -