TY - GEN AU - Marcel A.G.van der Heyden AU - Brian P.Delisle AU - Hugues Abriel AU - Baoxin Li TI - Ion Channel Trafficking and Cardiac Arrhythmias SN - 978-2-88945-643-7 PY - 2018/// PB - Frontiers Media SA KW - Kv11.1 channels KW - Connexin43 (Cx43) KW - ion channel KW - arrhythmia KW - TRPM4 channel KW - Glycosylation KW - NaV1.5 channels KW - Kir2.1 channels KW - trafficking KW - Autophagy KW - Protein complexes N1 - Open Access N2 - A well-adjusted expression of cardiac ion channels at the sarcolemma is of crucial importance for normal action potential formation and thus cardiac function. The cellular processes that transport channel proteins from the endoplasmic reticulum towards specified regions on the sarcolemmal membrane, and subsequently take them from the plasma membrane to the protein degradation machinery are commonly known as trafficking. The research field recognizes that aberrant channel trafficking stands at the basis of many congenital and acquired arrhythmias. The collection of papers in this eBook provides state-of-the-art insight into the world of ion channel trafficking research UR - https://www.frontiersin.org/research-topics/5514/ion-channel-trafficking-and-cardiac-arrhythmias UR - https://directory.doabooks.org/handle/20.500.12854/50657 ER -