TY - GEN AU - Rajabi,Taleieh TI - Entwicklung eines mikrofluidischen Zweikammer-Chipsystems mit integrierter Sensorik für die Anwendung in der Tumorforschung SN - KSP/1000041112 PY - 2014/// PB - KIT Scientific Publishing KW - membrane KW - Krebszellen KW - SensorikCancer cell KW - Metastasierung KW - Mikrofluidik KW - Blutgefäß KW - sensors KW - Membran KW - Blood vessel KW - Impedanz KW - microfluidic KW - Impedance N1 - Open Access N2 - We have developed a microfluidic two-layered channel system based on polycarbonate to investigate the transmigration of cancer cells under flow conditions and defined shear rate using live cell microscopy. The two layers are separated by a porous membrane with an endothelial monolayer on top of the membrane to mimic the blood vessel wall. To extend the measuring capabilities of our microfluidic chip, gold electrodes were structured on the membrane using optical lithography and chemical etching UR - https://www.ksp.kit.edu/9783731502203 UR - https://directory.doabooks.org/handle/20.500.12854/46581 ER -