TY  - GEN
AU  - Williams,Kenneth R.
AU  - Nairn,Angus C.
TI  - Neuroproteomics
SN  - books978-3-03928-107-7
PY  - 2020///
PB  - MDPI - Multidisciplinary Digital Publishing Institute
KW  - n/a
KW  - analgesia
KW  - quantitative phosphoproteomics
KW  - neurodegeneration
KW  - neuron
KW  - neuronal circuits
KW  - mating
KW  - sex-specific differences
KW  - AMPA receptor complex
KW  - parallel reaction monitoring
KW  - splicing
KW  - phosphorylation
KW  - peptidylglycine ?-amidating monooxygenase
KW  - pherophorin
KW  - Alzheimer’s disease
KW  - neuroscience
KW  - yohimbine
KW  - synapses
KW  - adolescence
KW  - conformational antibody
KW  - opioid receptors
KW  - protein interaction networks
KW  - Alzheimer’s Disease
KW  - transmembrane AMPA receptor regulatory protein
KW  - neuroproteome
KW  - ethanol
KW  - U1 snRNP
KW  - mass spectroscopy
KW  - morphine
KW  - protein phosphatase-1
KW  - neuroproteomics
KW  - axons
KW  - reinstatement
KW  - DIA
KW  - voltage gated channels
KW  - prohormone convertase
KW  - postsynaptic density
KW  - neuroimmune
KW  - dendrites
KW  - carboxypeptidase
KW  - GPCR signaling
KW  - CaMKII
KW  - FGF14
KW  - SynCAM
KW  - nicotinic receptor
KW  - synaptic plasticity
KW  - plasma
KW  - serum
KW  - corticosterone
KW  - dopamine
KW  - Receptor-type tyrosine-protein phosphatase zeta
KW  - Ptprz1
KW  - PRM
KW  - cell type
KW  - schizophrenia
KW  - laser capture microdissection
KW  - synapse specificity
KW  - LC-MS/MS
KW  - mouse
KW  - drug abuse
KW  - synaptic cleft
KW  - striatum
KW  - Cadm
KW  - cytokine
KW  - spinophilin
KW  - PSD
KW  - trans-synaptic adhesion
KW  - nicotine
KW  - proximity labeling
KW  - biomarkers
KW  - addiction
KW  - PKA
KW  - synapse
KW  - proteome
KW  - signal peptide
KW  - ventral tegmental area
KW  - protein aggregation
KW  - cerebrospinal fluid
KW  - bioinformatics
KW  - progressive ratio
KW  - interactome
KW  - subtilisin
KW  - affinity chromatography
KW  - basal ganglia
KW  - cocaine
KW  - targeted proteomics
KW  - postsynaptic
KW  - mass spectrometry
KW  - connectome
KW  - quantitative mass spectrometry
KW  - biotinylation
KW  - proteomics
KW  - amphetamine
KW  - autism
KW  - data-independent acquisition
KW  - excitatory/inhibitory tone
KW  - neuropeptidomics
KW  - matrix metalloproteinase
KW  - cilia
KW  - R-PTP-zeta
KW  - cognitive impairment
N1  - Open Access
N2  - The Neuroproteomics Special Issue overviews the unique challenges that must be addressed to carry out meaningful MS/proteomics analyses on neural tissues and the technologies that are available to meet these challenges. The articles on Alzheimer’s disease, addiction, and schizophrenia illustrate how MS/proteomics technologies can be used to improve our ability to diagnose and understand the molecular basis for neurological diseases. Several articles will be of interest to investigators beyond the field of neurological disorders. The review on the discovery of biofluid biomarkers of neurodegenerative dementias will be of interest to investigators searching for other disease biomarkers. Similarly, the review on the role of neuroproteomics in elucidating mechanisms of drug addiction provides an overview of the utility of MS/proteomics approaches for addressing critical questions in addiction neuroscience that should be applicable to investigators involved in virtually any area of biomedical research. Likewise, the article on developing targeted MS approaches for quantifying postsynaptic density proteins will be useful for any investigator who wishes to design targeted assays for virtually any protein. Finally, the peroxidase-mediated proximity labeling technology, described in the article on mapping the proteome of the synaptic cleft, will be of interest to investigators interested in mapping other spatially restricted proteomes
UR  - https://mdpi.com/books/pdfview/book/2022
UR  - https://directory.doabooks.org/handle/20.500.12854/54529
ER  -