TY  - GEN
AU  - Giuseppe Pignataro
TI  - Mechanisms of Innate Neuroprotection
SN  - 978-2-88919-929-7
PY  - 2016///
PB  - Frontiers Media SA
KW  - Neuroprotection
KW  - postconditioning
KW  - NCX
KW  - Stroke
KW  - seizure
KW  - miRNA
KW  - Alzheimer
KW  - preconditioning
N1  - Open Access
N2  - As clinical trials of pharmacological neuroprotective strategies in stroke have been disappointing, attention has turned to the brain's own endogenous strategies for neuroprotection. Two endogenous mechanisms have been recently characterized, ischemic preconditioning and ischemic postconditioning. In the present topic newly characterized mechanisms involved in preconditioning- and postconditioning- neuroprotection will be discussed. The understanding of the mechanisms involved in the neuroprotective pathways induced by preconditioning and postconditioning will be clinically relevant for identifying new druggable target for neurodegenerative disorder therapy. Furthermore, the importance of these neuroprotective strategies resides in that it might be easily translatable into clinical practice. Therefore, the data presented here will highlight the capacity of ischemic preconditioning and postconditioning to be of benefit to humans
UR  - http://journal.frontiersin.org/researchtopic/2693/mechanisms-of-innate-neuroprotection
UR  - https://directory.doabooks.org/handle/20.500.12854/52944
ER  -