Metal Metabolism in Animals
- MDPI - Multidisciplinary Digital Publishing Institute 2018
- 1 electronic resource (X, 356 p.)
Open Access
Through evolution of life, animals have adapted to the ubiquitous presence of metals in the biosphere. They utilize the more frequent ones as essential constituents of their biochemical machinery. In fact, about 40% of all proteins present in animal cells are so-called metalloproteins. On the other hand, animals have invented regulatory and detoxifying mechanisms to protect themselves from critical concentrations of both essential and non-essential metal concentrations. Metallomics is a modern approach applying cellular, biochemical, molecular and analytical methods to investigate the relationships of metals in their cellular context. The present edition contains a number of original articles and reviews dealing with various aspects of metallomics in animals, published as Special Issues of the International Journal of Molecular Sciences in 2016 and 2017. The book addresses subjects such as metal definition in biology, metabolism of metals in invertebrate and vertebrate animals, metal detoxification and regulation strategies, supplementation of essential trace elements, metal behavior in pregnancy and embryonic development, as well as metal toxicology and emerging medical implications.
Creative Commons
English
9783038428442 9783038428435
Allergy Protein Biochemistry Oxidative Stress Metalloprotein Homeostasis Metal Uptake Iron Metal Synthase Immunity Accumulation Model Organism Methylmercury Development Metal Toxicity Essential Trace Element Copper Protection Molecular Methods Metal Supplementation Binding Specificity Cadmium Transgenic Organisms T Cells Non-Essential Trace Element Animal Model Hypersensitivity Detoxification Tolerance Histology Palladium Metalloenzyme Stress Zinc Regulation Nickel Protein Disease Mercury Phytochelatin Metallothionein Apoptosis Cancer