TY  - GEN
AU  - Tettelin,Hervé
AU  - Medini,Duccio
AU  - Tettelin,Hervé
AU  - Medini,Duccio
TI  - The Pangenome : Diversity, Dynamics and Evolution of Genomes
SN  - 978-3-030-38281-0
PY  - 2020///
CY  - Cham
PB  - Springer Nature
KW  - Microbiology (non-medical)
KW  - bicssc
KW  - Evolution
KW  - Applied mathematics
KW  - Ecological science, the Biosphere
KW  - Medical genetics
KW  - Genetics (non-medical)
KW  - Microbial Genetics and Genomics
KW  - Evolutionary Biology
KW  - Genetics and Population Dynamics
KW  - Microbial Ecology
KW  - Human Genetics
KW  - Genetics and Genomics
KW  - Comparative genomics
KW  - Metagenomics
KW  - Microbial Population Analysis
KW  - Pangenome Profile
KW  - Supra-Genome Analysis
KW  - Adaptive Evolution
KW  - Computational Tools
KW  - Bioinformatic Genomics
KW  - Core Dispensable Genome
KW  - Selection, Recombination, Composition
KW  - Acquired Resistance
KW  - Bacterial Species Concept
KW  - Genomic Diversity
KW  - Bacterial Ecology, Microevolution
KW  - Open Access
KW  - Pan-metagenomics
KW  - Pan-microbiomics
KW  - Pan-epigenome
KW  - Gene Transfer
KW  - Pan-phenomes
N1  - Open Access
N2  - This open access book offers the first comprehensive account of the pan-genome concept and its manifold implications. The realization that the genetic repertoire of a biological species always encompasses more than the genome of each individual is one of the earliest examples of big data in biology that opened biology to the unbounded. The study of genetic variation observed within a species challenges existing views and has profound consequences for our understanding of the fundamental mechanisms underpinning bacterial biology and evolution. The underlying rationale extends well beyond the initial prokaryotic focus to all kingdoms of life and evolves into similar concepts for metagenomes, phenomes and epigenomes. The book’s respective chapters address a range of topics, from the serendipitous emergence of the pan-genome concept and its impacts on the fields of microbiology, vaccinology and antimicrobial resistance, to the study of microbial communities, bioinformatic applications and mathematical models that tie in with complex systems and economic theory. Given its scope, the book will appeal to a broad readership interested in population dynamics, evolutionary biology and genomics
UR  - https://library.oapen.org/bitstream/20.500.12657/37707/1/2020_Book_ThePangenome.pdf
UR  - https://directory.doabooks.org/handle/20.500.12854/31839
ER  -