TY - GEN AU - Downie,Laura AU - Lawrenson,John TI - Nutrition and Eye Health SN - books978-3-03921-991-9 PY - 2020/// PB - MDPI - Multidisciplinary Digital Publishing Institute KW - polyphenols KW - n/a KW - crocin KW - chyrsin KW - glaucoma KW - dietary assessment KW - photoreceptor degeneration KW - dry eye KW - RR-zeaxanthin KW - nutritional supplements KW - drug discovery KW - corneal neovascularization (CNV) KW - AMD KW - dietary antioxidants KW - micronutrients KW - age-related macular degeneration KW - preclinical models KW - lenses KW - microvascular lesions KW - cyclooxigenase-2 (COX-2) KW - angiogenesis KW - fish oil KW - macrophage KW - anti-oxidant KW - vascular endothelial growth factor (VEGF) KW - rosmarinic acid KW - visual cycle KW - diabetic retinopathy KW - lutein KW - gut-retina axis KW - light damage KW - crocetin KW - supplements KW - clinical practice guidelines KW - nutrition KW - light KW - eye disease KW - dietary habits KW - flavonoids KW - phytoconstituents KW - saffron KW - carotenoids KW - fatty acid KW - electroretinography KW - lens KW - advanced glycation end products KW - interleukin-1? (IL-1?) KW - mesozeaxanthin (RS zeaxanthin) KW - endoplasmic reticulum stress KW - omega-3 polyunsaturated fatty acids KW - clinical survey KW - corneal chemical burn KW - reduced glutathione KW - omega-3 KW - AGREE II KW - retina KW - inflammation KW - anti-inflammatory KW - retinal pigment epithelium KW - diet KW - Lactobacillus paracasei KW3110 KW - Crocus Sativus L KW - saponins KW - cataract KW - CODS KW - neoangiogenesis KW - estrogen-deficient rats KW - food frequency questionnaire KW - gut microbiota KW - antioxidant supplements KW - sinapic acid KW - personalised medicine KW - systematic reviews KW - nuclear factor-kappaB (NF-?B) KW - diabetes KW - Cucurbita argyrosperma KW - oxidative stress KW - endoplasmic reticulum N1 - Open Access N2 - Blindness and visual impairment impact significantly on an individual’s physical and mental well-being. Loss of vision is a global health problem, with approximately 250 million of the world’s population currently living with vision loss, of which 36 million are classified as blind. Visual impairment is more frequent in the elderly, with cataract and age-related macular degeneration (AMD) accounting for over 50% of cases globally. Oxidative stress has been strongly implicated in the pathogenesis of both conditions, and consequently the role of nutritional factors, in particular carotenoids and micronutrient antioxidants, have been investigated as possible preventative or therapeutic strategies. Dry eye syndrome (DES) is one of the most common ophthalmic conditions in the world. DES occurs where the eye does not produce enough tears and/or the tears evaporate too quicklyleading to discomfort and varying degrees of visual disturbance. There has recently been a great deal of interest in the potential for oral or topical supplementation with essential fatty acids (EFAs), specifically omega-3 and omega-6 fatty acids, as an adjunct to conventional treatments for DES. The objective of this Special Issue on ‘Nutrition and Eye Health’ is to publish papers describing the role of nutrition in maintaining eye health and the use of nutritional interventions to prevent or treat ocular disease. A particular (but not exclusive) emphasis will be on papers (reviews and/or clinical or experimental studies) relating to cataract, AMD and DES UR - https://www.mdpi.com/books/pdfview/book/1918 UR - https://directory.doabooks.org/handle/20.500.12854/54960 ER -