Francesco Moccia (Ed.) <br/><br/>
Calcium Signaling in Human Health and Diseases 

 -  MDPI - Multidisciplinary Digital Publishing Institute  2019 
 - 1 electronic resource (462 p.) 
<br/><br/> Open Access 
<br/><br/> Intracellular Ca2+ signaling is witnessing an amazing resurgence of interest. In addition to traditional Ca2+ aficionados, an astonishing (and growing) number of colleagues from all around the world have started to devote a large part of their research to gain insights into the role of Ca2+ signaling in health and disease. This is why calcium ions interact with virtually every signal transduction pathway not only in mammalian cells, but also across the phylogenetic tree, thereby, driving or modulating most, if not all, cellular functions, ranging from fertilization to apoptosis, passing through learning and memory, cardiac contractility, and immune response. This book gathers a collection of original research articles and reviews by a number of renowned experts who aim to present the state of the art of many pathophysiological aspects of intracellular Ca2+ signaling, such as embryonic development, immune response, extracellular Ca2+ signaling, neoplastic transformation, muscle hypertrophy, pulmonary inflammation, and P2X receptor gating. 
<br/><br/><br/>Creative Commons 
<br/><br/><br/>English 
<br/><br/><label>ISBN: </label>books978-3-03897-538-0 9783038975380 9783038975373 
<br/><br/><label>Standard No.: </label>10.3390/books978-3-03897-538-0  doi 
<br/><br/><label>Subjects--Index Terms: </label>STIM intracellular Ca2+ oscillations Ca2+ signaling 5-trisphosphate receptors neurovascular coupling cardiac contractility inositol-1 SERCA NMDA receptors calcineurin Orai P2X receptors Ca2+-Sensing Receptor 4 immune response cancer Ca2+-activated K+ channels muscle hypertrophy ryanodine receptors