Thomas J. Anastasio <br/><br/>
Computational and Experimental Approaches in Multi-Target Pharmacology 

 -  Frontiers Media SA  2017 
 - 1 electronic resource (122 p.) 
<br/><br/> Open Access 
<br/><br/> The next frontier in pharmacology is the development of multi-target strategies in which pathological processes are controlled by pharmacologically manipulating them at many different points at once. Designing multi-target strategies will require deep understanding of the complex physiology that underlies pathological processes. It will also require the development of single drugs with multiple targets, or combinations of drugs with compatible pharmacokinetics that work synergistically to maximize desirable effects while minimizing unwanted side effects. This e-Book contains ten original articles, each addressing a different aspect of this challenge. Together they open new perspectives and show the way forward in the development of multi-target therapeutics. 
<br/><br/><br/>Creative Commons 
<br/><br/><br/>English 
<br/><br/><label>ISBN: </label>978-2-88945-252-1 9782889452521 
<br/><br/><label>Standard No.: </label>10.3389/978-2-88945-252-1  doi 
<br/><br/><label>Subjects--Index Terms: </label>systems biology computer modeling drug repurposing synergy drug discovery drug combination high throughput screening multidrug therapeutics polypharmacy multifactorial process