Dmitrenok, Pavel S. <br/><br/>
Dedicated to the 55th Anniversary of G.B. Elyakov Pacific Institute of Bioorganic Chemistry of the Far Eastern Branch of the Russian Academy of Sciences 

 - Basel, Switzerland  MDPI - Multidisciplinary Digital Publishing Institute  2021 
 - 1 electronic resource (234 p.) 
<br/><br/> Open Access 
<br/><br/> The G.B. Elyakov Pacific Institute of Bioorganic Chemistry of the Far-Eastern Branch of the Russian Academy of Sciences (PIBOC FEB RAS) was founded in 1964 in Vladivostok in the Far East of Russia. Over many years, we have been carrying out studies on the natural products of both marine and terrestrial origin. In collaboration with many Russian and foreign scientists, we have investigated many hundreds of diverse biomolecules, including steroids and terpenoids, quinoid compounds and alkaloids, polysaccharides and lipids, enzymes and lectins, proteins, and peptides. The Institute has a collection of marine microorganisms (KMM) PIBOC, which includes more than 4000 strains of marine bacteria and more than 1000 strains of marine fungi. The biological activity of natural compounds is also being studied. This book includes the 14 manuscripts which covered almost all aspects of PIBOC research activity in the fields of bioorganic chemistry, biochemistry, organic synthesis of natural compounds, marine microbiology, and genetic engineering, and we hope it will provide interesting new information for scientists working in these fields. 
<br/><br/><br/>Creative Commons 
<br/><br/><br/>English 
<br/><br/><label>ISBN: </label>books978-3-0365-2505-1 9783036525044 9783036525051 
<br/><br/><label>Standard No.: </label>10.3390/books978-3-0365-2505-1  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Research & information: general
<br/><br/><label>Subjects--Index Terms: </label>polyhydroxylated steroids NMR spectra starfish Anthenoides laevigatus cytotoxicity soft agar assay kainic acid domoic acid dysiherbaine neodysiherbaine A marine bacteria whole genome sequence porin amino acids composition bilayer lipid membrane pore-forming activity spatial structure phlorotannins phlorethols anticancer activity colorectal cancer radiosensitizer radiotherapy 1,4-naphthoquinones quinoid compounds thioglycosides quinone-sugar conjugates cytotoxic activity antibiotic activity histochrome echinochrome A oxidative degradation HPLC–DAD–MS NMR actinoporin sea anemone Heteractis crispa anti-migratory activity glycosphingolipids cerebrosides peroxidation products structure elucidation allylic thioether ESI-MS GC-MS mass spectra glass sponge isomalabaricanes Stelletta sp. marine sponge terpenoid Cobetia amphilecti Cobetia litoralis Cobetia pacifica Cobetia marina Cobetia crustatorum identification markers alkaline phosphatase PhoA lanosterol 14-alpha demethylase flavonoids enzyme inhibition surface plasmon resonance spectral titration molecular docking Zobellia genomes polysaccharide lyase family 7 alginate utilization system paralogs orthologs recombinant phospholipase A1 Yersinia pseudotuberculosis inclusion bodies fusion protein green fluorescent protein porin gene expression antibiotic stress phenotypic heterogeneity n/a