TY  - GEN
AU  - Angeloni,Cristina
AU  - Vauzour,David
AU  - Angeloni,Cristina
AU  - Vauzour,David
TI  - Natural Products and Neuroprotection
SN  - books978-3-03936-217-2
PY  - 2020///
CY  - Basel, Switzerland
PB  - MDPI - Multidisciplinary Digital Publishing Institute
KW  - Research & information: general
KW  - bicssc
KW  - Biology, life sciences
KW  - Vitamin D
KW  - Multiple Sclerosis
KW  - symptom
KW  - neurodegeneration
KW  - oxidative injury
KW  - Parkinson’s disease
KW  - terpenes, rotenone
KW  - thymol
KW  - Alzheimer’s disease
KW  - Centella asiatica
KW  - hippocampus
KW  - protein poshophatase 2
KW  - glycogen synthase kinase 3
KW  - B-cell lymphoma 2
KW  - neuroprotection
KW  - nutraceuticals
KW  - bioavailability
KW  - stress response
KW  - neurodegenerative disease
KW  - bioactive compound
KW  - natural extract
KW  - β-amyloid peptide
KW  - tau protein
KW  - clinical trial
KW  - human studies
KW  - animal studies
KW  - in vitro studies
KW  - curcumin
KW  - free radicals
KW  - heme oxygenase
KW  - safety profile
KW  - type 2 diabetes
KW  - inflammation
KW  - vascular damage
KW  - learning
KW  - memory
KW  - natural compound
KW  - oxidative stress
KW  - cognitive dysfunction
KW  - cell death
KW  - synapse loss
KW  - protein aggregation
KW  - neuroinflammation
KW  - algae
KW  - seaweeds
KW  - neurodegenerative diseases
KW  - auraptene
KW  - dopamine neuron
KW  - antioxidant
KW  - mitochondria
KW  - Chionanthus retusus
KW  - flavonoid
KW  - flower
KW  - HO-1
KW  - NO
KW  - Lippia citriodora
KW  - VEE
KW  - Vs
KW  - relaxation
KW  - depression
KW  - cyclic AMP
KW  - calcium
KW  - blood–brain barrier
KW  - catechin
KW  - cognition
KW  - epigallocatechin gallate
KW  - green tea
KW  - microbiota
KW  - 5-(3,5-dihydroxyphenyl)-γ-valerolactone
KW  - ascaroside pheromone
KW  - C. elegans
KW  - dauer
KW  - neuronal signaling
KW  - sexual behavior
KW  - survival signals
KW  - proteostasis
KW  - chaperones
KW  - autophagy
KW  - ubiquitin-proteasome
KW  - unfolded protein response
KW  - natural compounds
KW  - natural products
KW  - ethics
KW  - patients’ autonomy
KW  - beneficence
KW  - nonmaleficence
KW  - medical liability
KW  - Parkinson’s disease (PD)
KW  - mitochondrial dysfunction
KW  - dynamics
KW  - hormesis
KW  - ubiquitin‒proteasome system (UPS)
KW  - mitophagy
KW  - n/a
N1  - Open Access
N2  - Neurodegenerative diseases, including Alzheimer’s, Parkinson’s, Huntington’s, and amyotrophic lateral sclerosis, are the most common pathologies of the central nervous system currently without a cure. They share common molecular and cellular characteristics, including protein misfolding, mitochondrial dysfunction, glutamate toxicity, dysregulation of calcium homeostasis, oxidative stress, inflammation, and ageing, which contribute to neuronal death. Efforts to treat these diseases are often limited by their multifactorial etiology. Natural products, thanks to their multitarget activities, are considered promising alternatives for the treatment of neurodegeneration. This book deals with two different forms of natural products: extracts and isolated compounds. The study of the bioactivity of the extracts is extremely important as many studies have demonstrated the synergistic effect of the combination of different natural products. On the other hand, the investigation of the activity of specifically isolated natural products can be also important to understand their cellular and molecular mechanisms and to define the specific bioactive components in extracts or foods. This book can be considered an important contribution to knowledge of the neuroprotective effect of natural products and presents a great deal of information, related to both the benefits but also the limitations of their use in counteracting neurodegeneration
UR  - https://mdpi.com/books/pdfview/book/2401
UR  - https://directory.doabooks.org/handle/20.500.12854/68639
ER  -