TY - GEN AU - Koulaouzidis,Anastasios AU - Marlicz,Wojciech AU - Koulaouzidis,Anastasios AU - Marlicz,Wojciech TI - Diagnosis and Treatment of Small Bowel Disorders SN - books978-3-03943-874-7 PY - 2021/// CY - Basel, Switzerland PB - MDPI - Multidisciplinary Digital Publishing Institute KW - Research & information: general KW - bicssc KW - Biology, life sciences KW - capsule endoscopy KW - Crohn’s disease KW - mucosal healing KW - small bowel KW - gut brain axis KW - microbiota KW - functional gastrointestinal disorders KW - inflammatory bowel disease (IBD) KW - adult stem cells KW - surgical site infections (SSIs) KW - probiotics KW - prebiotics KW - synbiotics KW - surgery KW - adverse events KW - meta-analysis KW - systematic review KW - hyperspectral imaging KW - multispectral imaging KW - clinical diagnosis KW - biomedical optical imaging KW - gastroenterology KW - medical diagnostic imaging KW - small-bowel mass KW - small-bowel bulge KW - video capsule endoscopy KW - cystic fibrosis KW - gut microbiota KW - intestinal inflammation KW - fecal calprotectin KW - dysbiosis index KW - celiac disease KW - biomarker KW - serology KW - enteropathy KW - n/a KW - colon cancer KW - cancer risk KW - collagenous colitis KW - lung cancer KW - microscopic colitis KW - skin cancer KW - squamous cell carcinoma N1 - Open Access N2 - Over the last few decades, remarkable progress has been made in understanding the aetiology and pathophysiology of diseases and many new theories emphasize the importance of the small bowel ‘ecosystem’ in the pathogenesis of acute and chronic illness. Emerging factors such as microbiome, stem cells, innate intestinal immunity and the enteric nervous system along with mucosal and endothelial barriers have key role in the development of gastrointestinal and extra-intestinal diseases. Therefore, the small intestine is considered key player in metabolic disease development, including diabetes mellitus, and other diet-related disorders such as celiac and non-celiac enteropathies. Another major field is drug metabolism and its interaction with microbiota. Moreover, the emergence of gut-brain, gut-liver and gut-blood barriers points toward the important role of small intestine in the pathogenesis of common disorders, such as liver disease, hypertension and neurodegenerative disease. However, the small bowel remains an organ that is difficult to fully access and assess and accurate diagnosis often poses a clinical challenge. Eventually, the therapeutic potential remains untapped. Therefore, it is due time to direct our interest towards the small intestine and unravel the interplay between small-bowel and other gastrointestinal (GI) and non-GI related maladies UR - https://mdpi.com/books/pdfview/book/3353 UR - https://directory.doabooks.org/handle/20.500.12854/68343 ER -