TY - GEN AU - Chatgilialoglu,Chryssostomos TI - Biomimetic Radical Chemistry and Applications SN - books978-3-03928-393-4 PY - 2020/// PB - MDPI - Multidisciplinary Digital Publishing Institute KW - gold nanoparticles KW - inhomogeneous reactions KW - chemical nuclease KW - liposomal somatostatin KW - replication fork stalling KW - lipid bilayer membranes KW - 2c-3e S?S-bonded intermediates KW - cell micropolarity maps KW - protein labeling KW - time-resolved spectroscopy KW - 1 KW - pulse radiolysis KW - nucleosides KW - 2-thiouracil KW - [1 KW - lipidomics KW - radicals KW - reactive aldehydes KW - iron porphyrin KW - photolysis KW - oxidative damage KW - free fatty acids KW - charge transfer KW - fragmentation KW - biomimetic radical reaction KW - sulfones KW - bioinspired chemical catalysis KW - genomic and epigenomic instability KW - ATRPase KW - DNA methylation KW - oxononenal KW - trans lipid KW - copper KW - membrane fluidity maps KW - mitochondrial uncoupling protein KW - heme KW - thiyl radicals KW - oxidation KW - anomeric spironucleosides KW - protein stability KW - laser flash photolysis KW - type 2 diabetes KW - stationary radiolysis KW - confocal microscopy KW - iron(IV)-oxo KW - 5]-radical translocation KW - diabetes KW - DNA hole transfer KW - free radical oxidation KW - radical reaction KW - kinetic studies KW - circular dichroism KW - catalase activity KW - thiobases KW - intercalation KW - electron transfer KW - iron-mediated ATRP KW - Fenton reaction KW - EPR spectroscopy KW - glycogen phosphorylase KW - azidoalkylation KW - free radicals KW - gamma radiolysis KW - quantum dynamics KW - hydrogen peroxide KW - carboazidation KW - ?OH and ?N3 radicals KW - 5? KW - oligonucleotides KW - Raman spectroscopy KW - azides KW - peroxidation KW - photo-ionization KW - guanine quadruplexes KW - 8-cyclopurines KW - beta cells KW - cross-link KW - miRNAs KW - oxidative DNA damage KW - DNA damage KW - modified nucleosides KW - Julia–Kocienski olefination KW - DNA oxidation KW - therapeutic proteins KW - DNA replication stress KW - electron holes KW - singlet oxygen KW - radiosensitizers KW - cellular response KW - hydroxynonenal KW - isomerization KW - ?-radiolysis KW - histone modifications KW - 8-oxo-dG KW - 6-dioxa-4-azaspiro[4.5]decane KW - retarded delivery KW - reaction mechanism KW - DNA KW - albumin KW - TD-DFT methods KW - nucleobase derivatives KW - bio-mimicking catalyst N1 - Open Access N2 - The enormous importance of free radical chemistry for a variety of biological events, including ageing and inflammation, has attracted a strong interest in understanding the related mechanistic steps at the molecular level. Modelling the free radical chemical reactivity of biological systems is an important research area. When studying free-radical-based chemical mechanisms, biomimetic chemistry and the design of established biomimetic models come into play to perform experiments in a controlled environment that is suitably designed to be in strict connection with cellular conditions. This Special Issue gives the reader a wide overview of biomimetic radical chemistry, where molecular mechanisms have been defined and molecular libraries of products are developed to also be used as traces for the discovery of some relevant biological processes. Several subjects are presented, with 12 articles and 6 reviews written by specialists in the fields of DNA, proteins, lipids, biotechnological applications, and bioinspired synthesis, having “free radicals” as a common denominator UR - https://mdpi.com/books/pdfview/book/2134 UR - https://directory.doabooks.org/handle/20.500.12854/42284 ER -